Results 41 to 50 of about 5,441,485 (301)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
European Investment Bank Activity Report 2021
, 2022 Our flagship report illustrates how the European Investment Bank Group confronted two great threats in 2021, the climate crisis and the coronavirus pandemic, even as the challenges posed by development grew more urgent.
European Investment Bank
core +1 more source
Management of the investment activities of the mining industry [PDF]
E3S Web of Conferences, 2020 The paper studies the main directions of investment activities of mining enterprises within the framework of the industrial development program. The principles of investment activities of mining enterprises have been substantiated, which are correlated ...
Filipishyna Liliia +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
ASPECTS REGARDING THE FINANCIAL INCLUSION OF THE JOINT STOCK COMPANIES [PDF]
Economica, 2016 The financial inclusion has become a subject of considerable interest among policy makers,researchers and other stakeholders. In international forums, such as the Group of Twenty (G-20), financial inclusion is on the top list of the reform agenda ...
Ana LITOCENCO
doaj
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
MiFID II – Analysis of Selected Issues Arising from the New Regulatory Package [PDF]
Societas et Iurisprudentia, 2016 MiFID II and MiFIR were adopted in the light of the financial crisis in order to enhance the investor protection and to ensure transparent trading. Both referred to as MiFID II, they replace former MiFID I and cover securities, investment intermediaries,
Filip Oller
doaj
On Development of American-Chinese Trading Relations
Евразийская интеграция: экономика, право, политика, 2020 The article is devoted to the analysis of the of American-Chinese trading relations’ development at the present stage. The economic strategies of the USA and China towards each other in the period up to 2016 are investigated and the changes that have ...
S. N. Pogodin, T. S. Yagya
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
, 2019 The chapters in this Ph.D. thesis explore three key issues on the topic of active investing. The first chapter discusses how to empirically test rational asset pricing models developed to explain asset pricing anomalies. The second chapter analyzes the costs and benefits of taking short positions when executing anomaly investing in equities.
openaire +1 more source