Results 41 to 50 of about 2,551,240 (307)
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Modelling of net flows to investment funds
The paper presents the general model of net flows to investment funds, which helps to analyse the flows and to solve the problem structurally. The model includes various investment guidelines and different fund types, aspects of risk influence are ...
Leonas Simanauskas +2 more
doaj +1 more source
Express evaluation methods for creating small and medium business projects
In this study the authors analyzed the problems associated with organizing private business and startup project appraisal for public and private funding.
Stepanchuk Andrey, Burova Ekaterina
doaj +1 more source
Investment Analysis of New Inpatient Wards Project at Ulin Hospital of Banjarmasin [PDF]
Adequate health care in a province is one of the primary needs that cannot be neglected. These needs will affect the health and life expectancy of the population of the province.
Aliludin, A. (Arson) +1 more
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Which projects are selected for an innovation subsidy? The Portuguese case [PDF]
Several empirical studies have analyzed which firm characteristics influence government evaluators in the decision to select specific firms to participate in Research and Develop- ment and Innovation subsidy programs. However, few authors have provided a
Cincera, Michele +3 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
An Options Approach to Cybersecurity Investment
Cybersecurity has become a key factor that determines the success or failure of companies that rely on information systems. Therefore, investment in cybersecurity is an important financial and operational decision.
Michail Chronopoulos +2 more
doaj +1 more source
Data Envelopment Analysis Models of Investment Funds [PDF]
Publisher ...
Lamb, John Douglas, Tee, Kai-Hong
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