Results 41 to 50 of about 270,935 (290)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Certain Aspects of Interstate Activity of International Centre for Settlement of Investment Disputes

Vestnik RUDN. International Relations, 2011
The article examines notion, concept and structure of International Centre for Settlement of Investment Disputes as well as certain aspects of its activities.
A V Kozmenko
doaj  

What is the Problem with Investment Disputes? The Case of the Draft Legislative Guide on Investment Dispute Prevention and Mitigation

AJIL Unbound
Embedded in any policy proposal is a set of assumptions about the problem that the policy is intended to solve.1 As policy processes play out, some of these assumptions are contested by the actors involved, while others remain latent.
Jonathan Bonnitcha
doaj   +1 more source

Procedural requirements for the application of the Denial of Benefits Clause in investment arbitration: Why is it hard to say no? [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu, 2019
International treaties for the protection and encouragement of foreign investments represent kind of a bargain by which a host State of the investment agrees to provide the investor of the other contracting party with particular substantive-law ...
Đundić Petar M.
doaj  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Certain Aspects of Structure and Functions of International Centre for Settlement of Investment Disputes

RUDN Journal of Political Science, 2011
The article examines notion, concept and structure of International Centre for Settlement of Investment Disputes as well as certain aspects of its activities.
A V Kozmenko
doaj  

The “Invisible” Local Communities: Foreign Investor Obligations, Inclusiveness, and the International Investment Regime

AJIL Unbound, 2019
International investment law is relational. It is about how we define and govern the relationship between the actors involved in and affected by foreign investment projects.
Nicolás M. Perrone
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Protection of Intellectual Property Rights in Investor-State Arbitration: Underlying Challenges and Perspectives

Kyiv-Mohyla Law and Politics Journal, 2021
This article provides an analysis of existing international mechanisms for protecting intellectual property rights and concludes whether investment arbitration can be an effective forum for resolving intellectual property disputes.
Kateryna Lazarchuk, Oksana Zadniprovska
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source