Results 41 to 50 of about 1,250,342 (317)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Study on the driving mechanism and risk hedging effect of economic policy uncertainty on digital transformation of agricultural enterprises

Frontiers in Sustainable Food Systems
Agriculture constitutes an essential cornerstone of national security. The digital transformation of agricultural enterprises is a pivotal driver in promoting agricultural modernization, enhancing industrial competitiveness, and ensuring food security ...
Wenwen Wang, Jingwen Jia
doaj   +1 more source

CORPORATE SOCIAL RESPONSIBILITY DISCLOSURE, INVESTMENT EFFICIENCY, INNOVATION, AND FIRM VALUE

Assets: Jurnal Akuntansi dan Pendidikan, 2021
This research purpose is to analyze the effect of Corporate Social Responsibility Disclosure on the value of environmentally risky companies, as those in agricultural, primary industry and chemicals, mining, property, real estate, and building ...
Dien Ajeng Fauziah, Eko Ganis Sukoharsono, Erwin Saraswati   +2 more
doaj   +1 more source

Insider Ownership and Investment Efficiency

SSRN Electronic Journal, 2020
ABSTRACTThis study examines the relationship between insider ownership and investment efficiency in Indian publicly listed firms, utilising panel data spanning 2001 to 2015. It explores how agency conflicts contribute to suboptimal capital investment decisions.
openaire   +4 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Board Bias, Information, and Investment Efficiency

SSRN Electronic Journal, 2021
Abstract We identify a novel force behind the benefit of misaligned preferences in corporate governance. Our model entails a CEO who encounters a project and, after gathering information, decides whether to seek the approval of a corporate board.
Gregor, Martin, Michaeli, Beatrice
openaire   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Carbon Emission Intensity and Investment Efficiency in the European Union: The Moderating Role of Analyst Coverage and Environmental Innovation

Ekonomi, Politika & Finans Araştırmaları Dergisi
This study examines the impact of carbon emission intensity (CEI) on investment efficiency (IE) as well as the moderating role of analyst coverage and environmental innovation in this relationship for firms operating in the European Union (EU).
Muhammet Kocaman, Elif Akben Selçuk
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

ECONOMIC ESSENCE OF MODERN INVESTMENT PROCESSES IN THE GRAIN PROCESSING INDUSTRY

Baltic Journal of Economic Studies, 2015
The subject of the research is theoretical and methodological bases of formation of effective investment in priorities feed processing industry in Ukraine.
Inna Kanashkina
doaj