Results 31 to 40 of about 1,033,005 (312)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Capital-protected funds with fixing of realized appreciations

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2005
Capital-protected funds of collective investments can be adequate investment opportunity for higher risk aversion investors with lower liquidity requirements. These funds always guarantee mostly 100% investment recovery and an appreciation sometimes.
Roman Ptáček
doaj   +1 more source

Investment funds as a form of effective pension protection in an aging society [PDF]

open access: yesScientific Journal of the Military University of Land Forces, 2020
The article aimed to analyze the effectiveness of investment funds and to create a ranking of investment funds with the highest economic efficiency. The scope of selection of the test sample is presented.
Agnieszka Parkitna   +3 more
doaj   +1 more source

Investment Styles, Fees, & Returns Among Individually Managed & Team Managed Mutual Funds [PDF]

open access: yes, 2011
Identifying a successful mutual fund investment involves a crucial analysis of alternatives, all of which influence the true benefit of the investment.
Cehanowicz, Kendal
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Investment Management Strategy in Financial Markets

open access: yesECONOMICS, 2018
The subject matter of this research is investment management and its forms practiced in developed financial markets. The goal of this research is to elaborate on the strategies and characteristics of investment companies, hedge funds, venture capital ...
Vunjak Nenad   +3 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

INVESTMENT PLATFORMS EVOLUTIONS – ETF FUNDS

open access: yesCopernican Journal of Finance & Accounting, 2017
Investment platforms, despite the short length of service on the Polish market, subject to continuous development. The nucleus of the creation of this product were the umbrella investment funds.
Karol Kraiński
doaj   +3 more sources

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