Results 31 to 40 of about 92,712 (263)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
PROBLEMS OF SELECTION AND EVALUATION OF INNOVATION AND INVESTMENT PROJECTS
Вестник Северо-Кавказского федерального университета, 2022 The article analyzes the methods of evaluation of innovation and investment projects and algorithm evaluation and selection of innovation and investment projects.
Mukhammat U. Baychorov
doaj
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
A New Cost in Measuring Investment Performance - Cost of Non – Intervention [PDF]
Risk in Contemporary Economy, 2019 The purpose of this paper is to present a new type of cost that should be taken into consideration in the process of evaluation. The cost proposed improves the accuracy of the final results of this process, concerning the opportunity for implementation ...
Andreea-Mariana Manta +2 more
doaj
Many-Criteria Evaluation of Infrastructure Investment Priorities for Distribution Network Planning
IEEE Access, 2020 With the liberalization of incremental distribution network investment business, more and more investment projects from various sources and diversified ownership are eligible for construction applications. This article proposes a many-criteria investment
Yidong Chen +6 more
doaj +1 more source
THE RISK PLANNING METHODOLOGICAL PRINCIPLES FOR HOUSING INVESTMENT
Three Seas Economic Journal, 2021 In many countries wordwide there is an urgent need to increase the housing level. However, a significant increase in this level is hindered by a number of factors.
Olena Balanska, Olexandr Yemelyanov
doaj +1 more source
Study on process evaluation and early warning technology of 35 kV and above power grid infrastructure project [PDF]
E3S Web of Conferences, 2020 The management requirements of internal quality and efficiency improvement of State Grid Corporation and the internal and external environment of strengthening external supervision have put forward higher requirements for investment management, and also ...
Gao Qian +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Наука и техника, 2016 Ever since the Soviet Union design solutions were evaluated according to different criteria and indicators. At the present stage of evaluation systems of design solutions stands systemengineering doctrine is allocated. It is complemented by the theory of
G. D. Kostsikava, G. V. Zemliakov
doaj +1 more source