Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening
Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker +3 more
wiley +2 more sources
Disability level and visibility: Associations with unmet academic accommodation needs and attitudes toward requesting accommodations. [PDF]
Christ BR +4 more
europepmc +1 more source
ABSTRACT Children experiencing parental imprisonment are known to be among the most overlooked in our community. They often experience multiple and compounding disadvantages, with long‐term consequences, but receive no specialised assistance. Knowledge about these children and their families is lacking in Australia and is required to inform policy ...
Catherine Flynn +6 more
wiley +1 more source
Bayesian optimization was used to optimize the synthesis parameters of the solid electrolyte Li7SiPS8$\mathrm {Li}_7\mathrm {SiPS}_8$ in order to increase the ionic conductivity. After only 32 iterations, the ionic conductivity was successfully increased from 2 to 7 mS cm−1$\mathrm {cm}^{-1}$ at 25∘C$^\circ\mathrm {C}$, while synthesis temperature and ...
Lucas G. Balzat +8 more
wiley +2 more sources
Protecting safety-net equity monitoring after federal sexual orientation and gender identity data rollbacks. [PDF]
Khurana D, Short A.
europepmc +1 more source
Barriers and Enablers for Effective Support Coordination in the National Disability Insurance Scheme
ABSTRACT Support coordinators act as intermediaries between the National Disability Insurance Scheme (NDIS) and participants, facilitating access to funded supports. To optimise outcomes, they must navigate NDIS complexities, identify services that meet individual needs and engage with diverse stakeholders.
Sharyn McDonald +3 more
wiley +1 more source
Statin-Induced Decade-Long Stabilization of Noncalcified Coronary Plaque Despite a Zero Calcium Score. [PDF]
Karlsberg RP.
europepmc +1 more source
Australia's Migration Strategy: An Effective Response to Migrant Worker Exploitation?
ABSTRACT A series of publicised migrant worker injuries and deaths has drawn attention to the issue of migrant worker exploitation (MWE) in Australia. In response, the Australian Government has included ‘Tackling Worker Exploitation’ as a key area of its Migration Strategy which it introduced in 2023. However, it is unclear how effective the Strategy’s
Evelyn Dowling, Alexandra Ridgway
wiley +1 more source
A metal‐free fluorinated ketazine‐linked COF is introduced as an efficient electrocatalyst for nitrate reduction to ammonia under neutral conditions. Fluorine substitution enhances π–π stacking and crystallinity, enabling a Faradaic efficiency of 59.9% and an NH3 yield rate of 1639.9 µmol h−1 mgCOF−1 at −0.9 V versus RHE. This establishes an unexplored
Islam E. Khalil +12 more
wiley +2 more sources
Terminating the Revolving Cycle of Silence: A Co-Production Study of a Media Campaign Intervention to Encourage Males Affected by Intimate Partner Violence Help-Seeking in Nigeria. [PDF]
Ike TJ +9 more
europepmc +1 more source

