Results 161 to 170 of about 480,275 (287)

Lipid Pocket Binders Impose Allosteric Changes of Protein Dynamics Around the Active Site of the Protein Kinase p38α

Angewandte Chemie International Edition, EarlyView.
Used in search of novel allosteric sites in the serine/threonine kinase p38α, NMR spectroscopy reveals a dynamic coupling between the catalytic and lipid pockets. The findings uncover a motional interdependence that links distant regions of the enzyme, highlighting the lipid pocket as a promising site for allosteric intervention.
Sara Medina Gómez, Laurin T. Homberg, Mike Bührmann, Daniel Rauh, Rasmus Linser   +4 more
wiley   +1 more source

Europe must act: a unified call to end complicity in the Gaza famine and genocide. [PDF]

Lancet Reg Health Eur
Blanchet K, Barakat S, Schmid B, Abrahim O, Abu-Sittah G.   +4 more
europepmc   +1 more source

More Than a Buffer in Biochemistry: Tris as an Architect and Gatekeeper of Metal–Oxo Assembly

Angewandte Chemie International Edition, EarlyView.
Tris(hydroxymethyl)aminomethane, depicted as an octopus, acts as an alkoxy ligand, chelator, and structure‐directing buffer that programs polyoxometalate's speciation, nucleation, and heterometal insertion in aqueous solution. ABSTRACT Polyoxometalates (POMs, molecular metal–oxo clusters) are typically studied and applied in aqueous media, where ...
Nadiia I. Gumerova, Annette Rompel
wiley   +1 more source

Ventricular arrhythmia in an elderly patient with renal cell carcinoma: seeing the invisible with cardiac magnetic resonance. [PDF]

J Geriatr Cardiol
Ching S, Wong KT.
europepmc   +1 more source

Effect of Temperature and Atmosphere on Agglomeration of Bed Particles in a Bubbling Fluidised Bed Burning Na‐Enriched Coal

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Agglomeration of bed materials during circulating fluidised bed (CFB) combustion or gasification of high‐alkali fuel is a practical challenge in industrial practice. This work investigates experimentally the effect of temperatures (700°C–900°C) and atmosphere (air equivalence ratios 1.61–0.53) on agglomeration in a lab‐scale bubbling fluidised
Zipeng Guo, Jianbo Li, Xiaofei Long, Quanhai Wang, Xiaofeng Lu   +4 more
wiley   +1 more source

What is this life if, full of care, we have no time to stand and stare? [PDF]

Br J Gen Pract
Papanikitas A.
europepmc   +1 more source

Toroidal‐Dipole‐Driven Polarization‐Selective Quasi‐BICs Enabling Wide‐Angle Near‐Field Image Display in Dielectric Metasurfaces

Advanced Physics Research, EarlyView.
This study presents toroidal‐dipole (TD)‐driven polarisation‐selective quasi‐bound states in the continuum (quasi‐BICs) in all‐dielectric metasurfaces, enabling transverse magnetic (TM)‐selective excitation with ultrahigh quality factors and wide‐angle‐stable polarisation‐dependent near‐field imaging.
Xueheng Yan, Dewang Huo, Haiyang Huang, Yang Jiao, Wei Li, Zengfeng Di   +5 more
wiley   +1 more source

Detection of MRI-Invisible Disease Using PSMA PET/CT in a Patient Considering Focal Therapy. [PDF]

Case Rep Urol
Jang JW, Abrams A, Jawahar A, Savas H, Yang XJ, Mehta V, Schnauss M, Schaeffer EM, Alam R, Ross AE.   +9 more
europepmc   +1 more source

Helmeted hornbill cranial kinesis: Balancing mobility and stability in a high‐impact joint

The Anatomical Record, EarlyView.
Abstract Prokinesis—in which a craniofacial joint allows the rostrum to move relative to the braincase—is thought to confer diverse advantages in birds, mostly for feeding. A craniofacial joint would, however, be a weak link if cranial stability is important. Paradoxically, we have identified a craniofacial joint in helmeted hornbills (Rhinoplax vigil),
Mike Schindler, Benjamin Flaum, Armita Razieh Manafzadeh, Viktoriia Kamska, Kanmani Chandra Rajan, Maria Jose Robles Malagamba, Ruien Hu, Daniel Baum, Mason N. Dean   +8 more
wiley   +1 more source

Older people care increases the gender gap in academia. [PDF]

Sci Rep
Vidal-Abarca MR, Martín-López B, Sala-Bubaré A, Anton-Pardo M, Catalan N, Freixa A, Lupon A, Nicolás-Ruiz N, Poblador S, Rodríguez-Lozano P, Sánchez-Montoya MDM, Suárez ML.   +11 more
europepmc   +1 more source