Results 191 to 200 of about 10,230 (219)

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Halogen bonding-induced 1,3-carbohydroxylation of allyl carboxylates <i>via</i> 1,2-cationic acyloxy migration (1,2-CAM). [PDF]

Chem Sci
Sharma S, Zhao G, Bedda L, Khosravi A, Musaev DG, Ngai MY.   +5 more
europepmc   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Generation of a Ground-State Electron Donor Utilizing Stored Light Energy. [PDF]

Chemistry
Taillefer M, Clot É, Prieto A.
europepmc   +1 more source

Synthesis, Physical and Ion-Conducting Properties of 1,2,3-Triazolium Ionic Liquids. [PDF]

Molecules
Abdelhedi Miladi I, Chikhaoui M, Alaa Eddine M, Serghei A, Ben Romdhane H, Drockenmuller E.   +5 more
europepmc   +1 more source

Downsizing Mo₆I₁₂ to Nanocrystals Unveils Visible-Light Photocatalytic Antibacterial Activity. [PDF]

Inorg Chem
Kubáňová M, Št'astný M, Bourhis E, Bezdička P, Tolasz J, Yao A, Halet JF, Ben Yahia M, Gautier R, Zelenka J, Lang K, Guégan R, Kirakci K.   +12 more
europepmc   +1 more source

Synthesis of (P^N^C)Gold(III) Complexes via Tandem Oxidative Addition/C-H Auration. [PDF]

ACS Org Inorg Au
Biedrzycki M, Martín J, Genoux A, Boschi E, Nevado C.   +4 more
europepmc   +1 more source

Catalytic Oxidative Ligand Transfer of Rh-Carbynoids and Alkyl Iodides. [PDF]

J Am Chem Soc
Esteve Guasch J, Pal D, Suero MG.
europepmc   +1 more source

Cobalt-Catalyzed Carbonylative Conversion of Unactivated Alkyl Chlorides. [PDF]

J Am Chem Soc
Xu C, Wang Y, Zeng G, Wu XF.
europepmc   +1 more source

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Fluoroalkyl Iodides in Fluoroalkylative Difunctionalization of C−C Multiple Bonds

Advanced Synthesis and Catalysis, 2023
Fatima Lucio-Martinez, Wojciech Chaładaj   +1 more
exaly