Results 71 to 80 of about 71,662 (334)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Indirect electrografting of aryl iodides

Electrochemistry Communications, 2019
The electrografting of 4-iodonitrobenzene that is not possible directly is demonstrated while that of 5-iodo-2-amino-pyridine, 4-iodoaniline and iodobenzene is performed with a decrease of overpotential >2 V.
Catherine Combellas, Frédéric Kanoufi, Jean Pinson, Fetah I. Podvorica   +3 more
doaj   +1 more source

The self-trapped hole in caesium halides [PDF]

, 1977
The equilibrium lattice configuration, electronic excitation energies and activation energies for hopping motion are calculated for a self-trapped hole in simple cubic CsCl, CsBr and CsI.
MONNIER, R, SONG, KS, STONEHAM, AM
core   +1 more source

Melaminium iodide monohydrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
In the title melaminium salt, 2,4,6-triamino-1,3,5-triazin-1-ium iodide monohydrate, C(3)H(7)N(6) (+)·I(-)·H(2)O, the components are linked via N-H⋯O, N-H⋯N, O-H⋯I and N-H⋯I hydrogen bonds. All of the H atoms of the melaminium cation are involved in hydrogen bonds. The melaminium cations are inter-connected by four N-H⋯N hydrogen bonds, forming ribbons
Min Min Zhao, Ping Ping Shi
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Low-Valent Tungsten Catalyzed Carbonylative Synthesis of Benzoates from Aryl Iodides and Alcohols

Molecules
Non-noble metals catalyzed carbonylative reactions serve as straightforward and sustainable methods for the synthesis of functionalized carbonyl-containing compounds.
Feihua Ye, Lin Lu, Zhaoyang Huang, Yunwei Huang, Lixuan Huang, Chunsheng Li, Xiang Li   +6 more
doaj   +1 more source

Conductance of electrolytes in 1-propanol solutions from −40 to 25°C [PDF]

, 1986
Conductance data for solutions of LiCl, NaBr, NaI, KI, KSCN, RbI, Et4NI, Pr4NI, Bu4NI, Bu4NClO4, n-Am4NI, i-Am4NI, n-Hept4NI, Me2Bu2NI, MeBu3NI, EtBu3NI, i-Am3BuNI, and i-Am3BuNBPh4 in 1-propanol at –40, –30, –20, –10, 0, 10, and 25°C are communicated ...
Barthel, Josef, Hilbinger, H., Schmeer, Georg, Wachter, R.   +3 more
core   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Sulfenamide-enabled ortho thiolation of aryl iodides via palladium/norbornene cooperative catalysis

Nature Communications, 2019
Poly-substituted aromatic sulfur compounds are part of many pharmaceuticals, agrochemicals and organic materials. Here, the authors developed a sulfenamide-enabled ortho-thiolation of aryl iodides via Pd/norbornene cooperative catalysis for the ...
Renhe Li, Yun Zhou, Ki-Young Yoon, Zhe Dong, Guangbin Dong   +4 more
doaj   +1 more source

Order-disorder phase transition driven by interlayer sliding in lead iodides

Nature Communications, 2023
2D layered materials attract interest due to their potential for application in nanoelectronics and optoelectronics. Here authors report an order-disorder-type phase transition driven by temperature in bulk lead iodides, and interlayer sliding is ...
Seyeong Cha, Giyeok Lee, Sol Lee, Sae Hee Ryu, Yeongsup Sohn, Gijeong An, Changmo Kang, Minsu Kim, Kwanpyo Kim, Aloysius Soon, Keun Su Kim   +10 more
doaj   +1 more source