Results 151 to 160 of about 210,084 (351)

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He   +6 more
wiley   +1 more source

Full-body deep learning-based automated contouring of contrast-enhanced murine organs for small animal irradiator CBCT [PDF]

open access: yesarXiv
Purpose. To alleviate the manual contouring burden, deep learning (DL) based automated contouring has been explored. However, due to the poor contrast resolution of preclinical irradiator CBCT, these methods have been limited to high contrast - minimally anatomically complex - structures such as the heart and lungs. Thus, low contrast abdominal CBCT DL-
arxiv  

Red‐Light‐Mediated Generation of Radicals: Applications in Organic Synthesis, Small‐Molecule Activation, Polymerization, and Bio‐Related Fields

open access: yesAngewandte Chemie International Edition, Accepted Article.
The field of visible light‐mediated photochemistry has experienced significant growth, leading to the development of a wide array of methodologies in synthetic organic chemistry. In particular, photocatalysis by using long‐wavelength light such as red and near‐infrared (NIR) light has garnered substantial attention recently.
Tong Zhang, Suman Pradhan, Shoubhik Das
wiley   +1 more source

ACCELERATION: Sequentially-scanning DECT Imaging Using High Temporal Resolution Image Reconstruction And Temporal Extrapolation [PDF]

open access: yesarXiv
Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with existing high-end DECT leveraging advanced X-ray source and/or detector technologies, the use of the sequentially-scanning data acquisition scheme to implement DECT may
arxiv  

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

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