Results 21 to 30 of about 89,029 (248)
The first 1000 days of life (the period between conception and the second birthday) is a window of opportunity for brain development, a unique period when the foundations for optimal growth and development of the nervous system are laid throughout the ...
Grigory A. Gerasimov
doaj +1 more source
Abstract Iodine deficiency has multiple adverse effects in humans, termed iodine deficiency disorders, due to inadequate thyroid hormone production. Globally, it is estimated that 2 billion individuals have an insufficient iodine intake, and South Asia and sub-Saharan Africa are particularly affected.
openaire +2 more sources
Is early disease detection always beneficial? What are the differences between Birds, Rabbits and Turtles? These and other questions under discussion in the De Gustibus column.
G A Gerasimov
doaj +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Review of the official medical statistics on prevalence and incidence on thyroid diseases in Russia made me feel sad. Not because it is too bad or showing trends that are threatening to public health.
Gregory Anatolievich Gerasimov
doaj +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Positions that were previously held in public life by impartial expertise, are now heavily shaken. In the era of the Internet, Wikipedia and social networks, the masses moved from the natural skepticism to the opinion of experts to actively ...
Gregory A. Gerasimov
doaj +1 more source
Iodine Speciation, Transportation, and Transformation in Soils: A Critical Review
BACKGROUND Identifying the occurrence form of iodine in soil and the law of iodine migration and transformation in soil is of great significance for evaluating the biogeochemical behavior of iodine and preventing human iodine deficiency diseases ...
CAO Han +3 more
doaj +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Trust but verify, or once again about evidence based medicine
In everyday life doctors have to verify whether they can trust certain diagnistic procedures and treatment methods. There are different study types that vary in terms of their validity.
Gregory A. Gerasimov
doaj +1 more source

