Results 201 to 210 of about 3,265,735 (388)

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

open access: yesAdvanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu   +20 more
wiley   +1 more source

Relativistic coupled cluster calculation of Mössbauer isomer shifts of iodine compounds [PDF]

open access: green, 2016
Tamar Zelovich   +3 more
openalex   +1 more source

Strong and Fatigue‐Resistant Hydrogels via Poor Solvent Evaporation Assisted Hot‐Stretching for Tendon Repair

open access: yesAdvanced Science, Volume 12, Issue 28, July 24, 2025.
An anisotropic hydrogel (AHs) is prepared in this study. The strength of AHs can reach up to 33.14 ± 2.05 MPa, and it exhibits unique defect‐insensitive characteristics. Cracks can only deflect along the fiber alignment direction, demonstrating an interesting self‐protection function.
Huamin Li   +11 more
wiley   +1 more source

Influence af acute iodine incorporation on thyroid function and thyroidal iodine content [PDF]

open access: yes, 1981
Habermann, J.   +4 more
core   +1 more source

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv   +8 more
wiley   +1 more source

Probing Anisotropic Quasiparticle Dynamics and Topological Phase Transitions in Quasi‐1D Topological Insulator ZrTe5

open access: yesAdvanced Science, EarlyView.
This study reveals quasiparticle dynamics in ZrTe5. Polarization‐dependent measurements show transient reflectivity anisotropy arises from electron relaxation and lattice vibrations. The first dynamical evidence of a temperature‐induced Lifshitz transition is reported.
Yueying Hou   +14 more
wiley   +1 more source

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