Results 191 to 200 of about 38,525 (307)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Modulatory Effects of Folic Acid and Dental Pulp Stem Cell‐Derived Exosomes on Gene Expression in a Periodontal Injury Model

Natural Sciences, Volume 6, Issue 2, April 2026.
Dental pulp stem cellderived exosomes and folic acid are evaluated for their effects on gene expression in an in‐vitro periodontal injury model. Human gingival fibroblasts subjected to oxidative and mechanical injury are treated with folic acid, exosomes, or their combination.
Saghar Zarei, Mostafa Montazeri, Nader Tanideh, Shahrokh Zare, Mahintaj Dara   +4 more
wiley   +1 more source

Protein Involved in Initiation 1 Interaction With Starch Synthase 4 From Arabidopsis thaliana Induces Inhibition of Elongating Activity

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 4, Page 973-986, April 2026.
ABSTRACT Starch is the major energy storage compound in plants. It accumulates in the form of insoluble, partly crystalline granules whose number and shape are specific to each plant species. These characteristics are defined very early in starch biosynthesis, at the initiation stage.
Mélanie Bossu, Rayan Osman, Guillaume Brysbaert, Marc Ferdinand Lensink, David Dauvillée, Coralie Bompard   +5 more
wiley   +1 more source

Computed Tomography Yield and Predictors of Pulmonary Embolism in Mechanically Ventilated Patients—A Retrospective Study

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 4, April 2026.
ABSTRACT Background The reported prevalence of pulmonary embolism (PE) detected during intensive care varies substantially. Computed tomography pulmonary angiography (CTPA) is the diagnostic reference method, but assessing pre‐test probability and finding distinct indications for CTPA from clinical observations is difficult in mechanically ventilated ...
Erik Bruno, Matilda Kewenter, Angeliki Dimopoulou Creusen, Freyr Einarsson, Gaetano Perchiazzi, Kristina Svennerholm, Christian Rylander   +6 more
wiley   +1 more source

Signal Amplification in the HPT Axis—Evidence for Its Existence, Location, Significance, and Molecular Mechanisms

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley   +1 more source

Prioritising research on endocrine disruption in the marine environment: a global perspective

Biological Reviews, Volume 101, Issue 2, Page 848-868, April 2026.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto, Angelica Miglioli, Carlie A. LaLone, Lisa Baumann, Alice Baynes, Mélanie Blanc‐Legendre, Ibon Cancio, Xavier Cousin, ZhiChao Dang, Rémi Dumollard, Alex T. Ford, Christopher Green, Taisen Iguchi, Philippa Kearney, Thomas Knigge, Christophe Minier, Tiphaine Monsinjon, Marta S. Monteiro, Joachim Sturve, Haruna Watanabe, Hiroshi Yamamoto, Gerald Ankley, Deborah M. Power, Ioanna Katsiadaki   +23 more
wiley   +1 more source

The Krakow Declaration on Iodine: Tasks and Responsibilities for Prevention Programs Targeting Iodine Deficiency Disorders. [PDF]

Eur Thyroid J, 2018
europepmc   +1 more source

Evaluating the Link Between Thyroid Function Test Results and Levothyroxine Dose in the Management of Hypothyroidism: Can We Improve Dosing Regimes?

Clinical Endocrinology, Volume 104, Issue 4, Page 372-385, April 2026.
ABSTRACT Introduction Over 10 million thyroid function tests (TFTs) are carried out in England each year, most requests coming from primary care. Our previous work showed that only 25% of results for patients being treated with Levothyroxine fell within the TSH/FT4 boundary circumscribing 75% of untreated individuals.
Adrian H. Heald, Lakdasa D. Premawardhana, Peter N. Taylor, Suhani Bahl, Onyebuchi E. Okosieme, Anthony A. Fryer, Antonio Bianco, Colin M. Dayan, Michael P. Stedman   +8 more
wiley   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 1955-1967, 15 March 2026.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source

Iodine deficiency and excess in children and related factors in Alborz Province: a cross-sectional study. [PDF]

BMC Nutr
Baladastian S, Bahreini F, Nouri A, Morvaridi M, Tavakoli H.   +4 more
europepmc   +1 more source