Effect of Maternal Iodine Excess during Pregnancy on Neonatal Thyroid Function and Neurodevelopmental Status at 12 Weeks. [PDF]
Rao DK +5 more
europepmc +1 more source
C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens +3 more
wiley +1 more source
Trends and Future Directions in Organic Chemistry for Drug Discovery
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley +1 more source
Cyclic Disulfide Sorting Influenced by Subtle Steric and Electronic Effects
The self‐assembly of two unsymmetrical dithiols to form cyclic disulfides are examined with an eye to the longitudinal equilibration behavior and directing agent effects on product distributions. Cyclic disulfide formation occurs in under 2 min, with full equilibration requiring up to 1 week.
Willow A. Davis +7 more
wiley +1 more source
Reversible Humidity‐Induced Vapochromism of a Cu(II) Tetramine Complex Driven by Iodide Access
A humidity‐responsive Cu(II) vapochromic complex based on reversible iodide coordination is reported. Unlike the chloride and bromide analogues, [Cu(chxn)2(H2O)2]I2 exhibits rapid and reversible color changes with humidity. Spectroscopic, diffraction, ESR, and DFT studies reveal that dehydration induces axial iodide coordination to form [Cu(chxn)2I2 ...
Masanori Wakizaka +4 more
wiley +1 more source
Total Synthesis and Absolute Configuration of the Irregular Tetraterpene Viaticene A
Viaticenes are tetraterpenes with a unique [6+2]‐connectivity from the springtail Hypogastrura viatica. Here, we report a modular 13‐step total synthesis of viaticene A, featuring stereoselective double‐bond formation, a Cu‐mediated allylic substitution, and Ni/Co‐cocatalyzed vinyl‐alkyl cross‐electrophile coupling as key steps.
Patrick Stamm +3 more
wiley +1 more source
A lumped modelling framework for the epoxidation of vegetable oils and fatty acid methyl esters
Abstract Epoxidized vegetable oils and fatty acid methyl esters are promising bio‐based alternatives to phthalates for plasticizer applications. Their synthesis typically involves the reaction of unsaturated double bonds with peracetic acid in a biphasic liquid–liquid system, where the simultaneous occurrence of reaction and phase partitioning makes ...
Irene Presti +3 more
wiley +1 more source
Learning Strategies from Nature's Blueprint to Cyclic Carbonate Synthesis
The development of sustainable synthetic methods for cyclic carbonates draws inspiration from nature, focusing on eco‐friendly processes and renewable resources like CO2 and biomass. This review explore various CO2 activation mechanisms, green chemistry principles, and green catalysts.
Erika Saccullo +4 more
wiley +1 more source
Recent Advance for PVDF Based Flexible Piezoelectric Sensors
This review focus on the structural regulation of PVDF via boundary confinement, blending regulation, electric‐field‐assisted orientation, and chemical modification for flexible piezoelectric sensors. ABSTRACT The rapid advancement of flexible electronics, wearable devices, and biomedical engineering has spurred increasing demand for sensor materials ...
Chaoran Tan +4 more
wiley +1 more source
Correction: Iodine deficiency and excess in children and related factors in Alborz Province: a cross-sectional study. [PDF]
Baladastian S +4 more
europepmc +1 more source

