Results 191 to 200 of about 2,584 (294)

The Versatility of Diazirines: Properties, Synthetic and Modern Applications

open access: yesChemistry – A European Journal, EarlyView.
Diazirines are 3‐membered heterocycles containing two nitrogen atoms connected by a double bond. They possess a multi‐faceted reactivity that holds great potential for organic synthesis. This review discusses their properties, modes of activation, and their many modern uses, underlining their underappreciated versatility: as carbene precursors, but ...
Mathieu L. Lepage, Emmanuel Gras
wiley   +1 more source

Tailored Watson–Crick Pairing Partners for Xanthosine in RNA

open access: yesChemistry – A European Journal, EarlyView.
RNAs with kappa‐xanthosine (K–X) or 2‐iminocytidine‐xanthosine (2imC–X) base pairs form stable double helices that have higher melting temperatures than those of the A–U or G–U references. Access to these novel 2imC‐modified RNAs is possible through the mild, selective chemical conversion of 2‐thiocytidine RNA precursors.
Stefan Mair   +5 more
wiley   +1 more source

Chloride Selective, Nonprotonophoric Ion Transport with Macrocyclic Halogen Bonding Anionophores

open access: yesChemistry – A European Journal, EarlyView.
Macrocyclic halogen bonding anionophores are reported, which enable very high chloride over proton and hydroxide transport selectivity. This ion selectivity profile is key for future potential therapeutic applications, and its origin is explored through DFT and MD simulations at the membrane.
Martin Flerin   +2 more
wiley   +1 more source

Iodine deficiency, hypothyroidism, and endemic goitre in Southern Tanzania [PDF]

open access: yes, 1985
Habermann, J.   +8 more
core  

Corn cob pyrolysis: A systematic literature review of methods and applications

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Mapping the research landscape of corn cob pyrolysis. Abstractas The agricultural sector is experiencing a surge in waste generation due to population growth, creating an urgent need to convert byproducts into value‐added products. Maize (Zea mays L.), a leading global crop, produces significant byproducts, such as corn cob, which are often undervalued.
Vilmar Steffen   +5 more
wiley   +1 more source

Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma

open access: yesChemMedChem, Accepted Article.
Glioblastoma (GBM) is the most common and aggressive malignant grade IV brain tumour and is one of the most difficult types of brain cancer to treat with a high incidence of resistance to traditionally used chemotherapeutics. Pyrazolopyrimidinones are fused nitrogen‐containing heterocyclic systems which are a scaffold in several bioactive drugs and ...
Kate Byrne   +5 more
wiley   +1 more source

A Mechanochemical Route for the Synthesis of Diphenyleneiodonium Salts and the Estimation of Their Relative Solid‐State Reactivities

open access: yesChemistry–Methods, EarlyView.
An efficient mechanochemical route for diphenyleneiodonium (DPI) salt synthesis is reported which offers a sustainable and solvent‐free alternative. The solid‐state reactivities of the reported DPI salts were also assessed with the help of morphology predictions and Hirshfeld surface analysis computations to understand the effect of crystal morphology,
Ipsha Shruti, Tejender S. Thakur
wiley   +1 more source

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