Results 21 to 30 of about 23,133 (214)

Iodo e Tiróide: O que o Clínico Deve Saber

Acta Médica Portuguesa, 2012
A Organização Mundial de Saúde considera a carência de iodo como a principal causa mundial evitável de doenças mentais e do desenvolvimento, estimando que cerca de 13% da população mundial esteja afectada por doenças causadas pela falta de iodo.
Maria Santana Lopes, João Jácome de Castro, Mafalda Marcelino, Maria João Oliveira, Francisco Carrilho, Edward Limbert   +5 more
doaj   +1 more source

Supramolecular Polymerization and Morphological Transformation of Dynamic Helical Poly(Phenylacetylene)s via Chain‐End Host–Guest Interactions

Angewandte Chemie, EarlyView.
A helical polymer whose chain ends are connected through pillar[5]arene‐based host–guest interactions translates molecular helicity into supramolecular morphology. Solvent‐triggered helicity inversion accompanied by changes in chain rigidity switches the supramolecular architecture between cyclic and rigid‐rod nanostructures.
Tatsuya Nishimura, Haru Nozue, Feng Li, Tomoki Ogoshi, Katsuhiro Maeda   +4 more
wiley   +2 more sources

Biotin‐ and Chloroalkane‐Modified Nucleotides for Dual Display of Proteins on DNA Through Streptavidin and Halotag Binding

Angewandte Chemie, EarlyView.
Modified 2’‐deoxy‐7‐deazaadenosine bearing a chlorohexyl moiety and 2’‐deoxycytidine nucleotides bearing biotin were used in the enzymatic synthesis of dually modified dsDNAs that served as scaffolds for display of halotag and monomeric streptavidin proteins.
Giammarco Liuni, Lenka Poštová Slavětínská, Miroslav Hájek, Veronika Raindlová, Michal Hocek   +4 more
wiley   +2 more sources

Dyotropic Rearrangement of Hypervalent Iodine Species: Migrative Heterofunctionalization of Quaternary Carbons

Angewandte Chemie, EarlyView.
1,2‐Aryl migration involving in situ‐generated alkyl iodine(III) species proceeds through a previously unrecognized 1,2‐C/I(III) dyotropic rearrangement. Migratory aryl fluorination, acetoxylation, and alkoxylation of 2‐alkyl‐2‐aryl‐3‐iodopropanoates provide α‐heterofunctionalized products, accompanied by aryl migration from the α‐ to the β‐position ...
Chen‐Xu Liu, Qian Wang, Matthew D. Wodrich, Jieping Zhu   +3 more
wiley   +2 more sources

T‐Shaped Stibenium(III) Cation: Hydrostibination Without Sb─H Bond

Angewandte Chemie, EarlyView.
A cationic, structurally constrained stibenium platform mediates anti‐Markovnikov hydrostibination of alkenes via element–ligand cooperativity (ELC), thereby bypassing the need for weak Sb─H bonds. ABSTRACT The hydrostibination of alkenes represents a largely underdeveloped transformation, owing to the intrinsic lability of the required Sb─H reagents ...
Ekta Nag, Lars Ole Busse, Andreas Albers, Manuel Schmitt, Lutz Greb   +4 more
wiley   +2 more sources

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Iodo(triphenyl)silane [PDF]

IUCrData, 2019
The molecular structure of the title compound, C18H15ISi, which crystallizes in the space group C2/c, does not exhibit any unusual features. Two weak C—H...π interactions may help to consolidate the packing. The present structure is not isostructural with the known Ph3SiX (X = F, Cl or Br) compounds.
Frauke Schödel, Hans-Wolfram Lerner, Timo Trageser, Michael Bolte   +3 more
openaire   +3 more sources

Aporte do Iodo nas Crianças das Escolas em Portugal

Acta Médica Portuguesa, 2012
Objectivo: Com o presente trabalho, pretendeu-se avaliar o aporte do iodo na população escolar portuguesa, a fim de transmitir às entidades responsáveis eventuais medidas a tomar.
Edward Limbert, Susana Prazeres, Márcia São Pedro, Deolinda Madureira, Ana Miranda, Manuel Ribeiro, Francisco Carrilho, J Jácome de Castro, Maria Santana Lopes, João Cardoso, Andre Carvalho, Maria João Oliveira, Henrique Reguengo, Fátima Borges, c Grupo de Estudos da Tiroide da Sociedade Portuguesa de Endocrinologia, Diabetes e Metaboli   +14 more
doaj   +1 more source

A Convenient Route to New (Radio)Fluorinated and (Radio)Iodinated Cyclic Tyrosine Analogs

Pharmaceuticals, 2022
The use of radiolabeled non-natural amino acids can provide high contrast SPECT/PET metabolic imaging of solid tumors. Among them, radiohalogenated tyrosine analogs (i.e., [123I]IMT, [18F]FET, [18F]FDOPA, [123I]8-iodo-L-TIC(OH), etc.) are of particular ...
Maria Noelia Chao, Jean-Michel Chezal, Eric Debiton, Damien Canitrot, Tiffany Witkowski, Sophie Levesque, Françoise Degoul, Sébastien Tarrit, Barbara Wenzel, Elisabeth Miot-Noirault, Audrey Serre, Aurélie Maisonial-Besset   +11 more
doaj   +1 more source

7-Iodo-3,3-diphenyloctahydrobenzofuran [PDF]

Acta Crystallographica Section E Structure Reports Online, 2013
The title compound, C20H21IO, was synthesized by cyclo-haloetherification of 2-(cyclo-hex-2-en-yl)-2,2-diphenyl-ethanol in CH2Cl2, and crystallized with two independent mol-ecules in the asymmetric unit. The six-membered cyclo-hexane ring adopts a chair conformation, while the five-membered ring adopts an envelope conformation with the fused C atom ...
Muhammad Sohail, Wang Yao-Feng, Wang Qi, Fu-Xue Chen   +3 more
openaire   +3 more sources