Results 21 to 30 of about 154 (113)

Model Optimization and In Silico Analysis of Potential Dipeptidyl Peptidase IV Antagonists from GC-MS Identified Compounds in Nauclea latifolia Leaf Extracts. [PDF]

Int J Mol Sci, 2019
Iheagwam FN, Ogunlana OO, Chinedu SN.
europepmc   +1 more source

Towards the Magic Radioactive Bullet: Improving Targeted Radionuclide Therapy by Reducing the Renal Retention of Radioligands. [PDF]

Pharmaceuticals (Basel)
de Roode KE, Joosten L, Behe M.
europepmc   +1 more source

Long-term changes in renal function and perfusion in heart failure patients with reduced ejection fraction. [PDF]

Clin Res Cardiol, 2016
Schroten NF, Damman K, Valente MA, Smilde TD, van Veldhuisen DJ, Navis G, Gaillard CA, Voors AA, Hillege HL.   +8 more
europepmc   +1 more source

In vitro pro-inflammatory enzyme inhibition and anti-oxidant potential of selected Sri Lankan medicinal plants. [PDF]

BMC Complement Altern Med, 2018
Perera HDSM, Samarasekera JKRR, Handunnetti SM, Weerasena OVDSJ, Weeratunga HD, Jabeen A, Choudhary MI.   +6 more
europepmc   +1 more source

Feasibility of measuring renal blood flow by phase-contrast magnetic resonance imaging in patients with autosomal dominant polycystic kidney disease. [PDF]

Eur Radiol, 2016
Spithoven EM, Meijer E, Borns C, Boertien WE, Gaillard CA, Kappert P, Greuter MJ, van der Jagt E, Vart P, de Jong PE, Gansevoort RT.   +10 more
europepmc   +1 more source

99mTc(CO)3(NTA) and 131I-OIH: comparable plasma clearances in patients with chronic kidney disease. [PDF]

J Nucl Med, 2013
Taylor AT, Lipowska M, Cai H.
europepmc   +1 more source

Hemodynamic and metabolic effects of estrogen plus progestin therapy in hypertensive postmenopausal women treated with an ACE-inhibitor or a diuretic. [PDF]

Clin Res Cardiol, 2015
Posadzy-Malaczynska A, Rajpold K, Woznicka-Leskiewicz L, Marcinkowska J.   +3 more
europepmc   +1 more source

Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination. [PDF]

European J Org Chem, 2017
Cavina L, van der Born D, Klaren PHM, Feiters MC, Boerman OC, Rutjes FPJT.   +5 more
europepmc   +1 more source

Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1. [PDF]

Mol Pharmacol, 2016
Esteva-Font C, Jin BJ, Lee S, Phuan PW, Anderson MO, Verkman AS.   +5 more
europepmc   +1 more source

A novel radioiodination reagent for protein radiopharmaceuticals with L- lysine as a plasma-stable metabolizable linkage to liberate m-iodohippuric acid after lysosomal proteolysis

A novel radioiodination reagent for protein radiopharmaceuticals with L- lysine as a plasma-stable metabolizable linkage to liberate m-iodohippuric acid after lysosomal proteolysis
Radiochemical design of polypeptides using metabolizable linkages would be attractive to enhance target-selective localization of radioactivity for diagnostic and therapeutic nuclear medicine. However, while use of ester bonds as the linkage allows selective release of the designed radiometabolite from covalently conjugated polypeptide after lysosomal ...
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