Results 61 to 70 of about 172 (123)

Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination. [PDF]

European J Org Chem, 2017
Cavina L, van der Born D, Klaren PHM, Feiters MC, Boerman OC, Rutjes FPJT.   +5 more
europepmc   +1 more source

A novel radioiodination reagent for protein radiopharmaceuticals with L- lysine as a plasma-stable metabolizable linkage to liberate m-iodohippuric acid after lysosomal proteolysis

A novel radioiodination reagent for protein radiopharmaceuticals with L- lysine as a plasma-stable metabolizable linkage to liberate m-iodohippuric acid after lysosomal proteolysis
Radiochemical design of polypeptides using metabolizable linkages would be attractive to enhance target-selective localization of radioactivity for diagnostic and therapeutic nuclear medicine. However, while use of ester bonds as the linkage allows selective release of the designed radiometabolite from covalently conjugated polypeptide after lysosomal ...
openaire  

Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1. [PDF]

Mol Pharmacol, 2016
Esteva-Font C, Jin BJ, Lee S, Phuan PW, Anderson MO, Verkman AS.   +5 more
europepmc   +1 more source

(99m)Tc(CO)3(NTA): a (99m)Tc renal tracer with pharmacokinetic properties comparable to those of (131)I-OIH in healthy volunteers. [PDF]

J Nucl Med, 2010
Taylor AT, Lipowska M, Marzilli LG.
europepmc   +1 more source

Renal function in glycogen storage disease type I, natural course, and renopreservative effects of ACE inhibition. [PDF]

Clin J Am Soc Nephrol, 2009
Martens DH, Rake JP, Navis G, Fidler V, van Dael CM, Smit GP.   +5 more
europepmc   +1 more source

Copeptin, a surrogate marker of vasopressin, is associated with disease severity in autosomal dominant polycystic kidney disease. [PDF]

Clin J Am Soc Nephrol, 2011
Meijer E, Bakker SJ, van der Jagt EJ, Navis G, de Jong PE, Struck J, Gansevoort RT.   +6 more
europepmc   +1 more source

Chemistry Department. Annual Report 1986 [PDF]

, 1987

core  

TSPO 18 kDa (PBR) Targeted Photosensitizers for Cancer Imaging (PET) and PDT. [PDF]

ACS Med Chem Lett, 2011
Chen Y, Sajjad M, Wang Y, Batt C, Nabi HA, Pandey RK.   +5 more
europepmc   +1 more source

The role of imaging with iodine-131-meta-iodobenzylguanidine in the diagnosis and localisation of suspected phaeochromocytoma [PDF]

, 2017
Adams, B K
core   +1 more source

99mTc(CO)3-nitrilotriacetic acid: a new renal radiopharmaceutical showing pharmacokinetic properties in rats comparable to those of 131I-OIH. [PDF]

J Nucl Med, 2009
Lipowska M, Marzilli LG, Taylor AT.
europepmc   +1 more source