Results 41 to 50 of about 99 (97)

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

Advanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang, Mingyue Fan, Su Chin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han   +13 more
wiley   +1 more source

OcuPair, a Novel Photo‐crosslinkable PAMAM Dendrimer‐Hyaluronic Acid Hydrogel Bandage/Bioadhesive for Corneal Injuries and Temporary Corneal Repair

Advanced Science, EarlyView.
A schematic diagram showing the OcuPair adhesive hydrogel formulation loaded into the final delivery device and applied over the full‐thickness corneal wound in an in vivo rabbit model of corneal injury followed by in situ crosslinking to form a transparent hydrogel bandage sealing the wound.
Siva P. Kambhampati, Rishi Sharma, Hui Lin, Santiago Appiani, Jeffrey L. Cleland, Samuel C. Yiu, Rangaramanujam M. Kannan   +6 more
wiley   +1 more source

New Insights into Heavy Metal Sequestration Through Metal‐Phenolic Network‐Confined Nano‐HFO: Overlooking Iron Utilization and Modulating Electron Density

Advanced Science, EarlyView.
Iron‐based nanocomposites are widely used for trace heavy metal removal, but the low utilization of HFO nanoparticles remains a challenge. Here, a metal‐phenolic network (MPN) strategy is proposed to confine nano‐HFO within polystyrene beads, creating a negative electrostatic field and optimizing electron density at oxygen sites. This approach enhances
Manyu Zhang, Xiaolin Du, Zhanqi Liu, Yujia Yang, Shuo Wang, Ningyi Chen, Yulin Wang, Yaran Song, Keju Sun, Qingrui Zhang   +9 more
wiley   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

Advanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou   +11 more
wiley   +1 more source

Nanoreactor‐Driven Uniform Nano ZnS Deposition in Tunable Porous Carbon Spheres for High‐Performance Zn‐S Batteries

Advanced Science, EarlyView.
In this work, a series of porous carbon spheres with tunable pore size, particle size, and shell thickness are designed as nanoreactors for the S‐ZnS redox reactions in Zn‐S batteries. The presence of abundant defects and oxygen‐containing functional groups facilitates efficient ion/electron transport throughout the reaction process, significantly ...
Yuxuan Jiang, Bingxin Sun, Dan Wang, Yan Yan, Mohsen Shakouri, Han‐Yi Chen, Wang Zhang, Rongmei Zhu, Huan Pang   +8 more
wiley   +1 more source

Solar‐Powered Hierarchical Microenvironments with Authigenic Multi‐Field Synergies for Simultaneous Extraction of Freshwater and Cesium

Advanced Science, EarlyView.
A biomass‐based solar‐powered hierarchical self‐extraction micro‐network (BSSM) is first proposed to achieve freshwater production and Cs+ extraction. This study establishes a transformative paradigm for resource recovery, providing a scalable and eco‐friendly panacea to address pressing global issues, including water scarcity, nuclear pollution, and ...
Liuyan Zhu, Lin Zhu, Ting Shi, Ke Zhao, Wenwen He, Lu Han, Zeying Jin, Jialin Kang, Shanfu Sun, Ningning Cao, Zhen Yu   +10 more
wiley   +1 more source

Thermo‐Responsive Tri‐State Photonic Crystals

Advanced Science, EarlyView.
Tri‐state photonic crystals combine thermochromic structural color, fluorescence, and afterglow via far‐field absorption tuning, bypassing the efficiency‐lifetime trade‐off of TS‐FRET. This enables dynamic, high‐capacity anti‐counterfeiting with tunable optical states.
Yuewei Zheng, Jinqing Chen, Wanqi Mo, Wei Hong   +3 more
wiley   +1 more source

Moisture Harvesting by the Structure Regulation of Hygroscopic Hydrogel for Energy and Water Sustainability

Advanced Electronic Materials, EarlyView.
Hygroscopic hydrogels are capable of utilizing the moisture from air, which can transfer the gaseous water to liquid by a surface phase transition. Taking advantage of this water, sustainable water production, thermal management, and electricity generation can be realized.
Yujie Du, Yongliang Zheng, Hong Liu, Shujing Zhao, Xiaomian Wang, Lin Yang   +5 more
wiley   +1 more source

Advanced Microfluidic‐Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring

Advanced Electronic Materials, EarlyView.
Microfluidic‐based wearable electrochemical sensors are transforming non‐invasive health monitoring through real‐time biochemical analysis of sweat, saliva, and interstitial fluid. This review explores advances in microfluidic design, fabrication, and sensor integration while addressing biofluid variability, material compatibility, and scalability.
Sehyun Park, Seongyeop Kim, Soojin Lee, Vladimir V. Tsukruk, SeungHyun Park, Hyo‐Ryoung Lim   +5 more
wiley   +1 more source