Results 41 to 50 of about 7,915,278 (376)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Biomedical Implants with Charge‐Transfer Monitoring and Regulating Abilities

open access: yesAdvanced Science, 2021
Transmembrane charge (ion/electron) transfer is essential for maintaining cellular homeostasis and is involved in many biological processes, from protein synthesis to embryonic development in organisms.
Donghui Wang   +4 more
doaj   +1 more source

Construction of Co–Mn Prussian Blue Analog Hollow Spheres for Efficient Aqueous Zn‐ion Batteries

open access: yesAngewandte Chemie, 2021
Prussian blue analogs (PBAs) are considered as reliable and promising cathode materials for aqueous Zn‐ion batteries (AZIBs), but they suffer from low capacity and poor cycling stability due to insufficient active sites and structural damage caused by ...
Yinxiang Zeng   +5 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Capabilities of Thomson parabola spectrometer in various laser-plasma- and laser-fusion-related experiments

open access: yesNukleonika, 2023
The Thomson parabola spectrometer (TPS) [1] is a well-known, universal diagnostic tool that is widely used in laser plasma experiments to measure the parameters of accelerated ions.
Tchórz Przemysław   +4 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Ion-Ion Interaction at the Multi-Ion TRPV1 Pore [PDF]

open access: yesBiophysical Journal, 2016
Proton released upon tissue injury, inflammation, or ischemia produces sustained pain that may be mediated by nociceptor TRPV1. Our previous study demonstrated that extracellular H+ not only activates the channel but also inhibits ion permeation. Voltage-dependence of H+ inhibition suggested that H+ moves halfway into the transmembrane electric field ...
Jie Zheng, Bo Hyun Lee
openaire   +2 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

An ion trap-ion mobility-time of flight mass spectrometer with three ion sources for ion/ion reactions [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2009
This instrument combines the capabilities of ion/ion reactions with ion mobility (IM) and time-of-flight (TOF) measurements for conformation studies and top-down analysis of large biomolecules. Ubiquitin ions from either of two electrospray ionization (ESI) sources are stored in a three dimensional (3D) ion trap (IT) and reacted with negative ions from
Gregg M. Schieffer   +6 more
openaire   +3 more sources

On the Hilbert series of vertex cover algebras of unmixed bipartite graphs [PDF]

open access: yes, 2010
We compute the reduced Gr\"{o}bner basis of the toric ideal with respect to a suitable monomial order and we study the Hilbert series of the vertex cover algebra $A(G)$, where $G$ is an unmixed bipartite graph without isolated vertices.Comment: 8 ...
Ion, Cristian
core  

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