Results 51 to 60 of about 5,779,106 (323)

Potentiometric Determination of Ascorbic acid,Malonic acid and Resorcinol Using Sulphide and Cyanide Ion-Selective Electrodes Compared with Platinum Electrode. [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
A new potentiometric method was adopted for the determination of ascorbic acid , malonic acid and resorcinol using iodine (dissolved in glacial acetic acid) as oxidant .
Ismail K.Al_Hitti, Nagham K. Kareem
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Why Civil and Criminal Procedure Are So Different: A Forgotten History [PDF]

open access: yes, 2017
Much has been written about the origins of civil procedure. Yet little is known about the origins of criminal procedure, even though it governs how millions of cases in federal and state courts are litigated each year.
Meyn, Ion
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

ION-BY-ION COOLING EFFICIENCIES

open access: yesThe Astrophysical Journal Supplement Series, 2012
Submitted to ApJS. Electronic data available at http://wise-obs.tau.ac.il/~orlyg/ion_by_ion/
Gnat, Orly, Ferland, Gary J.
openaire   +4 more sources

Ion channels [PDF]

open access: yesThorax, 2013
Effective therapies for the 10% of patients with 'severe' asthma remain elusive, while other pulmonary diseases such as idiopathic pulmonary fibrosis are currently untreatable. Many cellular processes rely heavily on signals delivered by changes in the intracellular-free Ca(2+) concentration, in many cases relying on Ca(2+) influx from the ...
Peter, Bradding, Heike, Wulff
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

ẢNH HƯỞNG CỦA THUỐC TRỪ SÂU DECIS LÊN ĐIỀU HÒA ÁP SUẤT THẨM THẤU VÀ TĂNG TRƯỞNG TÔM SÚ (PENAEUS MONODON)

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2010
Sử dụng thuốc trừ sâu để diệt tạp và kích thích tôm lột xác đã xuất hiện trong nghề nuôi tôm ở Đồng Bằng Sông Cửu Long dù không được khuyến cáo. Nghiên cứu được thực hiện nhằm xác định độ độc của thuốc trừ sâu decis chứa hoạt chất deltamethrin lên tôm ...
Nguyễn Thanh Phương   +3 more
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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