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Bacterial Ion Channels

Biochemistry, 2003
Fifteen years ago the presence of ion channels in the cytoplasmic membrane of bacteria was held by many to be inherently unlikely, given the prominent role played by the membrane in energy transduction. The presence of channels in the outer membrane of Gram negative bacteria was known and the physiological roles, structures and genetics were already ...
Michelle D. Edwards   +2 more
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Ion Channels in Plants

Physiological Reviews, 2012
Since the first recordings of single potassium channel activities in the plasma membrane of guard cells more than 25 years ago, patch-clamp studies discovered a variety of ion channels in all cell types and plant species under inspection. Their properties differed in a cell type- and cell membrane-dependent manner.
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Ion Channels of Microbes

2004
Electrophysiology and the study of ion channels has generally been the province of neurobiologists. However, since the application of patch clamp techniques to microbial membranes, it is evident that microbes possess a variety of ion channel activities. Microbial genome sequencing projects have revealed that, in fact, nearly all microbes that have been
Paul Blount   +6 more
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Ion-channel assembly

Trends in Neurosciences, 1995
Transmembrane ion channels regulate the movement of ions (particularly Na+, K+, Ca2+ and Cl-) across cellular membranes, and are critical to numerous aspects of neurobiology. Cells express a diverse array of ion-channel proteins that vary widely in their ion selectivity and in their modulation by ligands (such as neurotransmitters) or by membrane ...
Neil S. Millar, William N. Green
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Ion Channels in Yeast

Science, 1986
Voltage-dependent ion channels have been found in the plasma membrane of the yeast Saccharomyces cerevisiae . Ion channel activities were recorded from spheroplasts or patches of plasma membrane with the patch-clamp technique. The most prominent activities came from a set of potassium channels with the properties of
Michael C. Gustin   +4 more
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Ion Channels in Sperm

1995
Publisher Summary This chapter discusses the ion channels in sperm. The chapter mentions that the flow of ions through the plasma membrane of sperm, particularly Ca2+, participates crucially in the events leading to fertilization. Cell communication involves molecular mechanisms as they play a key role in determining the behavior of organisms.
A. Liévano, A. Darszon
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Reconstitution of Ion Channel

Critical Reviews in Biochemistry, 1985
The first model of the structure of cell membranes was developed very early from indirect evidence.' It postulated the existence of a bimolecular lipid membrane which serves as the main and electrical isolating part of the cell membrane. The proteins were either associated with or incorporated into the membrane.Z Following this idea, it was postulated ...
Wolfang Hanke, Christopher Miller
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Ion channels and epilepsy

American Journal of Medical Genetics, 2001
AbstractIon channels provide the basis for the regulation of excitability in the central nervous system and in other excitable tissues such as skeletal and heart muscle. Consequently, mutations in ion channel encoding genes are found in a variety of inherited diseases associated with hyper‐ or hypoexcitability of the affected tissue, the so‐called ...
Frank Lehmann-Horn   +2 more
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Ion channels in disease

Current Opinion in Pediatrics, 2001
Diseases as different as cardiac arrhythmias, epilepsy, myotonia, malignant hyperthermia, familial hyperinsulinism, and Bartter syndrome have all been linked to mutations in genes encoding ion channels. This has been made possible by an exciting and fruitful collaboration between clinicians, geneticists, and physiologists. It has led to a more detailed
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Ion channels in epilepsy

Biochemical Society Transactions, 2007
Neuronal excitability is determined by the flux of ions through ion channels. Many types of ion channels are expressed in the central nervous system, each responsible for its own aspect of neuronal excitability, from postsynaptic depolarization to action potential generation to neurotransmitter release.
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