Results 91 to 100 of about 1,568,609 (304)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Performance of Novel Randomly Oriented High Graphene Carbon in Lithium Ion Capacitors

open access: yesInternational Journal of Electrochemistry, 2018
The structure of carbon material comprising the anode is the key to the performance of a lithium ion capacitor. In addition to determining the capacity, the structure of the carbon material also determines the diffusion rate of the lithium ion into the ...
Rahul S. Kadam, Kishor P. Gadkaree
doaj   +1 more source

Ion beam sputter etching and deposition of fluoropolymers [PDF]

open access: yes
Fluoropolymer etching and deposition techniques including thermal evaporation, RF sputtering, plasma polymerization, and ion beam sputtering are reviewed. Etching and deposition mechanism and material characteristics are discussed.
Banks, B. A.   +3 more
core   +1 more source

Hydration interactions: aqueous solvent effects in electric double layers

open access: yes, 2000
A model for ionic solutions with an attractive short-range pair interaction between the ions is presented. The short-range interaction is accounted for by adding a quadratic non-local term to the Poisson-Boltzmann free energy.
A. P. Lyubartsev   +49 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Simulation study on the influence of initial density distribution of laser ionized plasma on the ion extraction characteristics

open access: yesAIP Advances
In isotope concentration technology, ion extraction current and ion extraction efficiency are the key factors to measure the efficiency of the isotope concentration.
Xing Chen, Xiao-Yong Lu, Lu Cai
doaj   +1 more source

Proton energy behavior by variation of the target density in laser acceleration

open access: yes, 2017
Ion acceleration using a laser pulse irradiating a thin disk target is examined using three-dimensional and two-dimensional particle-in-cell simulations. A laser pulse of $620$ TW, with an intensity of $5\times 10^{21}$ W/cm$^{2}$ and a duration time of $
Morita, Toshimasa
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Revealing the CME Impact on the Martian Nightside Ionosphere Based on MAVEN and Tianwen-1 Observations

open access: yesThe Astrophysical Journal
Due to the absence of an Earth-like dipole magnetic field, the impact of coronal mass ejections (CMEs) on the Martian nightside ionosphere differs from that on Earth and is still not well understood.
Longhui Liu   +8 more
doaj   +1 more source

Case studies of ion focusing in the downstream region of a modeled low Earth orbit spacecraft

open access: yesEarth and Planetary Physics
The effect of plasma and charged particle interaction with spacecraft in a low Earth orbit (LEO) environment leads to ion focusing and the formation of an ion void in the downstream region as a result of charging.
Nizam Ahmad   +6 more
doaj   +1 more source

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