Results 61 to 70 of about 360,268 (308)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Tunnel Manganese Oxides Prepared Using Recovered LiMn2O4 from Spent Lithium-ion Batteries : Co adsorption behavior and mechanism [PDF]
, 2022 The purpose of this study was to investigate Cobalt (Co) removal from wastewater using synthesized manganese oxides from the recovered LiMn2O4. An efficient ultrasonication leaching method was utilized to recycle LiMn2O4 from spent lithium-ion batteries (
Zhang, Yulai +4 more
core +1 more source
Next MaterialsPolyaniline (PANI) and titanium-based ion exchangers have garnered considerable attention due to their superior ion exchange characteristics in significant environmental applications, ion exchange membranes, and solid-state electrochemistry.
K. Jacinth Mispa, S. Santhanamari Jeya
doaj +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Effects of reaction ion kinetic energy on both endothermic and exothermic ion/molecule reactions in a quadrupole ion trap mass spectrometer [PDF]
, 2011 The effects of kinetic energy on the outcomes of exothermic and endothermic ion/molecule reactions in a quadrupole ion trap mass spectrometer are examined.
Wu, H. F. ; 吳慧芬; Brodbelt, J. S.
core +1 more source
Functionalized nonwoven Nylon fabrics for cadmium ion exchange applications
Engineering and Applied Science Research, 2020 Water pollution is a big issue of our world. This research aims to study the possibility of using carboxylate functionalized synthetic nonwoven fabrics for removing heavy metals from contaminated water.
Wichuda Chanprapanon, Nithinart Chitpong
doaj +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Fabrication of high-capacity protein ion-exchangers with polymeric ion-exchange groups grafted onto micron-sized beads by atom transfer radical polymerization [PDF]
, 2015 The static adsorption capacity for proteins is regarded as the benchmark for achieving high binding capacity in protein chromatography. This research provided an efficient and controlled approach for the synthesis of ion-exchange beads with high ...
Shi, Qing-Hong, Li, Shu, Sun, Yan
core +1 more source