Results 61 to 70 of about 968,741 (248)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Analisis Kinetika Pertukaran Ion NH4+ dan H+ pada Zeolit Alam Lampung dengan Shrinking Core Model

open access: yesJurnal Rekayasa Kimia & Lingkungan, 2009
Ion exchange process between ion NH4+ and H+ by using zeolite as its ion exchanger is one of methods to purify water from ammonium ion content. Natural zeolites are chosen as ion exchanger because it is abundantly provided in Indonesia, especially in ...
Simparmin Ginting
doaj   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Ion exchange fertilizers and ammoniated organic matter

open access: yesCalifornia Agriculture, 1962
California Agriculture - All ...
O Lunt, R Sciaroni, A Kofranek
doaj  

Ionization enhanced ion collection by a small floating grain in plasmas

open access: yes, 2011
It is demonstrated that the ionization events in the vicinity of a small floating grain can increase the ion flux to its surface. In this respect the effect of electron impact ionization is fully analogous to that of the ion-neutral resonant charge ...
Khrapak, Sergey A., Morfill, Gregor E.
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Fate and Impacts of Triclosan, Sulfamethoxazole, and 17β-estradiol during Nutrient Recovery via ion Exchange and Struvite Precipitation [PDF]

open access: yes, 2017
Increasing emphasis on resource recovery from wastewater highlights the importance of capturing valuable products, e.g., nutrients such as nitrogen and phosphorus, while removing contaminants, e.g., organic micropollutants. The objective of this research
Mayer, Brooke K.   +2 more
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Ion Transport Characteristics in Membranes for Direct Formate Fuel Cells

open access: yesFrontiers in Chemistry, 2020
Ion exchange membranes are widely used in fuel cells to physically separate two electrodes and functionally conduct charge-carrier ions, such as anion exchange membranes and cation exchange membranes.
Xiangyu Su, Zhefei Pan, Liang An
doaj   +1 more source

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