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Ion homeostasis in the Chloroplast
2014The chloroplast is an organelle of high demand for macro- and micro-nutrient ions, which are required for the maintenance of the photosynthetic process. To avoid deficiency while preventing excess, homeostasis mechanisms must be tightly regulated. Here, we describe the needs for nutrient ions in the chloroplast and briefly highlight their functions in ...
Marc Hanikenne +2 more
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Ion homeostasis in diabetic kidney disease
Trends in Endocrinology & MetabolismThe complications of type 2 diabetes are a major global public health problem with high incidence and mortality, affecting almost all individuals with diabetes worldwide. Diabetic kidney disease (DKD) is one such primary complication and has become a leading cause of end-stage renal disease in patients with diabetes. Progression from diabetes to DKD is
Hongtu Hu, Wei Liang, Guohua Ding
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Ion homeostasis and ion channels in NLRP3 inflammasome activation and regulation
Current Opinion in Immunology, 2018The NLRP3 inflammasome is a multiprotein platform for the activation of caspase-1, which in turn drives inflammation through the activation of proinflammatory cytokines, such as IL-1β. In contrast to the majority of pattern recognition receptors, NLRP3 inflammasome can be triggered by a plethora of pathogen-derived or endogenous activators, which ...
Iva, Hafner-Bratkovič, Pablo, Pelegrín
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The neurobiology of glia in the context of water and ion homeostasis
Neuroscience, 2004Astrocytes are highly complex cells that respond to a variety of external stimulations. One of the chief functions of astrocytes is to optimize the interstitial space for synaptic transmission by tight control of water and ionic homeostasis. Several lines of work have, over the past decade, expanded the role of astrocytes and it is now clear that ...
M, Simard, M, Nedergaard
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Golgi pH and Ion Homeostasis in Health and Disease
2020Maintenance of the main Golgi functions, glycosylation and sorting, is dependent on the unique Golgi pH microenvironment that is thought to be set by the balance between the rates of V-ATPase-mediated proton pumping and its leakage back to the cytoplasm via an unknown pathway.
Khosrowabadi Elham +1 more
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Ion and Fluid Homeostasis in the Cochlea
2017The transduction of sound into nerve impulses requires an ionic environment that depends on a variety of ion transport processes in epithelial and endothelial cells of the cochlea. Specific ion transport functions occur in specific cell types that coordinate the production and maintenance of endolymph, which is the fluid in the lumen of the cochlear ...
Philine Wangemann, Daniel C. Marcus
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Regulation of ion homeostasis under salt stress
Current Opinion in Plant Biology, 2003When under salt stress, plants maintain a high concentration of K(+) and a low concentration of Na(+) in the cytosol. They do this by regulating the expression and activity of K(+) and Na(+) transporters and of H(+) pumps that generate the driving force for transport.
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Imaging ion flux and ion homeostasis in blood stage malaria parasites
Biotechnology Journal, 2009AbstractThe steady‐state regulation of intracellular levels of essential ions and ionic gradients is critical for almost all functions within a cell. Thus, it is not surprising to find that ions have been shown to play an important role in numerous parasitic processes, such as invasion, development and possibly drug resistance mechanisms.
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