Results 11 to 20 of about 41,261 (264)

Integrating the potential of ion mobility spectrometry-mass spectrometry in the separation and structural characterisation of lipid isomers

open access: yesFrontiers in Molecular Biosciences, 2023
It is increasingly evident that a more detailed molecular structure analysis of isomeric lipids is critical to better understand their roles in biological processes.
Sandra M. Camunas-Alberca   +6 more
doaj   +1 more source

Identification of Tomato Infecting Viruses That Co-Isolate with Nanovesicles Using a Combined Proteomics and Electron-Microscopic Approach

open access: yesNanomaterials, 2021
Plant-derived nanovesicles (NVs) have attracted interest due to their anti-inflammatory, anticancer and antioxidative properties and their efficient uptake by human intestinal epithelial cells.
Ramila Mammadova   +11 more
doaj   +1 more source

Protein shape sampled by ion mobility mass spectrometry consistently improves protein structure prediction

open access: yesNature Communications, 2022
Collision cross sections (CCS) from ion mobility mass spectrometry provide information about protein shape and size. Here, the authors develop an algorithm to predict CCS and integrate experimental ion mobility data into Rosetta-based molecular modelling
SM Bargeen Alam Turzo   +7 more
doaj   +1 more source

Protein Biocargo and Anti-Inflammatory Effect of Tomato Fruit-Derived Nanovesicles Separated by Density Gradient Ultracentrifugation and Loaded with Curcumin

open access: yesPharmaceutics, 2023
Plant-derived nanovesicles (PDNVs) have become attractive alternatives to mammalian cell-derived extracellular vesicles (EVs) both as therapeutic approaches and drug-delivery vehicles.
Ramila Mammadova   +11 more
doaj   +1 more source

Ion Mobility-Mass Spectrometry and its Applications in Protein Glycosylation Research [PDF]

open access: yesZhipu Xuebao, 2022
Glycosylation is one of the most important post-translational modifications (PTM), mediating physiological processes like cell adhesion, cell proliferation, cell signaling, and immune responses.
FU Bin1, LIANG Yu-ying1, LU Hao-jie1,2
doaj   +1 more source

High-Pressure Ion Mobility Spectrometry [PDF]

open access: yesAnalytical Chemistry, 2009
The effects of above-ambient pressure on ion mobility on resolving power, resolution, and ion current were investigated using a small, stand-alone ion mobility spectrometer (IMS). This work demonstrates the first example of ion mobility spectrometry at pressures above ambient.
Eric J, Davis   +4 more
openaire   +2 more sources

Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations

open access: yesCommunications Biology, 2022
An optimized method for mass spectrometry based immunopeptidomics analysis using high-field asymmetric waveform ion mobility spectrometry is presented and identifies 44,815 HLA-bound peptides (HLAp) from colorectal cancer samples.
Yuriko Minegishi   +8 more
doaj   +1 more source

Ion mobility spectrometry: history, characteristics and applications

open access: yesRevista U.D.C.A Actualidad & Divulgación Científica, 2012
Ion mobility spectrometry (IMS) is an analytical technique that separates ions in the gas phase. Ions are separated at atmospheric pressure under the influence of an electric field, according to their size and shape.
Roberto Fernández Maestre
doaj   +1 more source

Comprehensive spectral libraries for various rabbit eye tissue proteomes

open access: yesScientific Data, 2022
Measurement(s) database type spectral library Technology Type(s) ion mobility spectrometry-mass spectrometry Sample Characteristic - Organism Oryctolagus cuniculus Sample Characteristic - Environment eye Sample Characteristic - Location United States of ...
Guoting Qin   +4 more
doaj   +1 more source

Recent Progress in Protein Stereochemical Modifications Revealed by Ion Mobility-Mass Spectrometry [PDF]

open access: yesZhipu Xuebao, 2022
Protein stereochemical modification (SCM) is a unique type of low-abundance post-translational modification associated with many human diseases. Because it does not change the molecular weight of proteins, traditional proteomics methods are generally not
XU Xia1   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy