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Fundamentals of ion mobility spectrometry [PDF]
Fundamental questions in ion mobility spectrometry have practical implications for analytical applications in general, and omics in particular, in three respects. (1) Understanding how ion mobility and collision cross section values depend on the collision gas, on the electric field and on temperature is crucial to ascertain their transferability ...
Gabelica, Valérie, Marklund, Erik
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Orthogonal extraction ion mobility spectrometry [PDF]
Ion Mobility Spectrometry is a powerful tool for the study of molecular conformations, separation of mass isomers, and analysis of complex mixtures and suppression of chemical background. The factors that limit the capabilities of the technique include its relatively low resolving power and duty cycle.
Laiko, Victor V.
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An Ion Mobility-Mass Spectrometry Imaging Workflow [PDF]
Mass spectrometry imaging (MSI) is a powerful technique for the label-free spatially-resolved analysis of biological tissues. Coupling ion mobility (IM) separation with MSI allows separation of isobars in the mobility dimension and increases confidence ...
Steve, Creger +5 more
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It is increasingly evident that a more detailed molecular structure analysis of isomeric lipids is critical to better understand their roles in biological processes.
Sandra M. Camunas-Alberca +6 more
doaj +1 more source
Plant-derived nanovesicles (NVs) have attracted interest due to their anti-inflammatory, anticancer and antioxidative properties and their efficient uptake by human intestinal epithelial cells.
Ramila Mammadova +11 more
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Ion mobility mass spectrometry of saponin ions [PDF]
Rationale Saponins are natural compounds presenting a high structural diversity whose structural characterization remains extremely challenging. Ideally, saponin structures are best established using nuclear magnetic resonance experiments conducted on isolated molecules.
Corentin Decroo +8 more
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Collision cross sections (CCS) from ion mobility mass spectrometry provide information about protein shape and size. Here, the authors develop an algorithm to predict CCS and integrate experimental ion mobility data into Rosetta-based molecular modelling
SM Bargeen Alam Turzo +7 more
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Collision-Induced Unfolding of Native-like Protein Ions Within a Trapped Ion Mobility Spectrometry Device [PDF]
Native mass spectrometry and collision-induced unfolding (CIU) workflows continue to grow in utilization due to their abil-ity to rapidly characterize protein conformation and stability.
Katherine, Graham +3 more
core +1 more source
Effect of Humidity on the Mobilities of Small Ions in Ion Mobility Spectrometry
Ions in the ion mobility spectrometry (IMS) are mostly hydrated. A single peak in the drift time spectrum is usually generated by a mixture of ions differing in the number of attached water molecules. Under real IMS detector operating conditions, ions change their composition during movement in the drift region due to the changes in the number of water
Izabela Wolańska +3 more
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S.1-9The purpose of the investigations reported was a feasibility study of field asymmetric ion mobility spectrometry (FAIMS) applications for the characterization of recovered wood. Especially the treatment with organic wood preservatives represented by
Gunschera, J. +4 more
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