Results 11 to 20 of about 43,067 (263)

Fundamentals of ion mobility spectrometry [PDF]

Current Opinion in Chemical Biology, 2018
Fundamental questions in ion mobility spectrometry have practical implications for analytical applications in general, and omics in particular, in three respects. (1) Understanding how ion mobility and collision cross section values depend on the collision gas, on the electric field and on temperature is crucial to ascertain their transferability ...
Gabelica, Valérie, Marklund, Erik
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Integrating the potential of ion mobility spectrometry-mass spectrometry in the separation and structural characterisation of lipid isomers

Frontiers in Molecular Biosciences, 2023
It is increasingly evident that a more detailed molecular structure analysis of isomeric lipids is critical to better understand their roles in biological processes.
Sandra M. Camunas-Alberca, Maria Moran-Garrido, Jorge Sáiz, Alberto Gil-de-la-Fuente, Alberto Gil-de-la-Fuente, Coral Barbas, Ana Gradillas   +6 more
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Identification of Tomato Infecting Viruses That Co-Isolate with Nanovesicles Using a Combined Proteomics and Electron-Microscopic Approach

Nanomaterials, 2021
Plant-derived nanovesicles (NVs) have attracted interest due to their anti-inflammatory, anticancer and antioxidative properties and their efficient uptake by human intestinal epithelial cells.
Ramila Mammadova, Immacolata Fiume, Ramesh Bokka, Veronika Kralj-Iglič, Darja Božič, Matic Kisovec, Marjetka Podobnik, Apolonija Bedina Zavec, Matej Hočevar, Gabriella Gellén, Gitta Schlosser, Gabriella Pocsfalvi   +11 more
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Ion mobility mass spectrometry of saponin ions [PDF]

Rapid Communications in Mass Spectrometry, 2018
Rationale Saponins are natural compounds presenting a high structural diversity whose structural characterization remains extremely challenging. Ideally, saponin structures are best established using nuclear magnetic resonance experiments conducted on isolated molecules.
Corentin Decroo, Emmanuel Colson, Vincent Lemaur, Guillaume Caulier, Julien De Winter, Gustavo Cabrera‐Barjas, Jérôme Cornil, Patrick Flammang, Pascal Gerbaux   +8 more
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Protein shape sampled by ion mobility mass spectrometry consistently improves protein structure prediction

Nature Communications, 2022
Collision cross sections (CCS) from ion mobility mass spectrometry provide information about protein shape and size. Here, the authors develop an algorithm to predict CCS and integrate experimental ion mobility data into Rosetta-based molecular modelling
SM Bargeen Alam Turzo, Justin T. Seffernick, Amber D. Rolland, Micah T. Donor, Sten Heinze, James S. Prell, Vicki H. Wysocki, Steffen Lindert   +7 more
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Protein Biocargo and Anti-Inflammatory Effect of Tomato Fruit-Derived Nanovesicles Separated by Density Gradient Ultracentrifugation and Loaded with Curcumin

Pharmaceutics, 2023
Plant-derived nanovesicles (PDNVs) have become attractive alternatives to mammalian cell-derived extracellular vesicles (EVs) both as therapeutic approaches and drug-delivery vehicles.
Ramila Mammadova, Serena Maggio, Immacolata Fiume, Ramesh Bokka, Maneea Moubarak, Gabriella Gellén, Gitta Schlosser, Giorgia Adamo, Antonella Bongiovanni, Francesco Trepiccione, Michele Guescini, Gabriella Pocsfalvi   +11 more
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Ion Mobility-Mass Spectrometry and its Applications in Protein Glycosylation Research [PDF]

Zhipu Xuebao, 2022
Glycosylation is one of the most important post-translational modifications (PTM), mediating physiological processes like cell adhesion, cell proliferation, cell signaling, and immune responses.
FU Bin1, LIANG Yu-ying1, LU Hao-jie1,2
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Ion mobility spectrometry: history, characteristics and applications

Revista U.D.C.A Actualidad & Divulgación Científica, 2012
Ion mobility spectrometry (IMS) is an analytical technique that separates ions in the gas phase. Ions are separated at atmospheric pressure under the influence of an electric field, according to their size and shape.
Roberto Fernández Maestre
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Effect of Humidity on the Mobilities of Small Ions in Ion Mobility Spectrometry

Analytical Chemistry, 2023
Ions in the ion mobility spectrometry (IMS) are mostly hydrated. A single peak in the drift time spectrum is usually generated by a mixture of ions differing in the number of attached water molecules. Under real IMS detector operating conditions, ions change their composition during movement in the drift region due to the changes in the number of water
Izabela Wolańska, Krzysztof Piwowarski, Edyta Budzyńska, Jarosław Puton   +3 more
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Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations

Communications Biology, 2022
An optimized method for mass spectrometry based immunopeptidomics analysis using high-field asymmetric waveform ion mobility spectrometry is presented and identifies 44,815 HLA-bound peptides (HLAp) from colorectal cancer samples.
Yuriko Minegishi, Kazuma Kiyotani, Kensaku Nemoto, Yoshikage Inoue, Yoshimi Haga, Risa Fujii, Naomi Saichi, Satoshi Nagayama, Koji Ueda   +8 more
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