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Ion mobility spectrometry

2004
Ion mobility spectrometry was developed for the simple and cheap detection and characterization of organic compounds (Cohen and Karasek, 1970; Karasek, 1970; Caroll et al., 1971; Caroll, 1972; Cohen et al., 1972; Cohen and Crowe, 1973; Vora et al., 1987; St. Louis and Hill, 1990; Campbell et al., 1991; Burke, 1992; Eiceman and Karas, 1994; Taylor, 1996;
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Hadamard Transform Ion Mobility Spectrometry

Analytical Chemistry, 2005
Traditionally, the spectrum acquired using ion mobility spectrometry (IMS) is an average of multiple experimental cycles. Each cycle is initiated by passing a short burst of ions into a drift tube containing a homogeneous electric field. Prior to starting the subsequent cycle, all ions in the system must arrive at the detector or spectral overlap may ...
Brian H, Clowers   +3 more
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Ion Mobility-Mass Spectrometry of Glycoconjugates

2019
Glycoconjugates are diverse biomolecules that are dynamically assembled to regulate and fine-tune numerous cellular processes. Their biosynthesis is nontemplate-driven, achieved stepwise in discrete locations within the cell, giving rise to a range of complex branched structures that pose a significant challenge in structural biology. Mass spectrometry
Weston B, Struwe, David J, Harvey
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Hadamard Transform Ion Mobility Spectrometry

Analytical Chemistry, 2006
A detection scheme that makes use of the Hadamard transform has been employed with an atmospheric-pressure ion mobility spectrometer fitted with an electrospray ionization source. The Hadamard transform was implemented through the use of a linear-feedback shift register to produce a pseudorandom sequence of 1023 points.
Andrew W, Szumlas   +2 more
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Fourier Transform Ion Mobility Spectrometry

Analytical Chemistry, 1985
Theorie du fonctionnement d'un spectrometre a deux portes.
F J, Knorr   +3 more
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Voltage Sweep Ion Mobility Spectrometry

Analytical Chemistry, 2011
Ion mobility spectrometry (IMS) is a rapid, gas-phase separation technique that exhibits excellent separation of ions as a standalone instrument. However, IMS cannot achieve optimal separation power with both small and large ions simultaneously. Similar to the general elution problem in chromatography, fast ions are well resolved using a low electric ...
Eric J, Davis   +3 more
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Surface Ionization Ion Mobility Spectrometry

Analytical Chemistry, 1998
A surface ionization (SI) source was designed and constructed for ion mobility spectrometry (IMS). Compared with a conventional (63)Ni source, the surface ionization source is as simple and reliable, has an extended dynamic response range, is more selective in response, and does not have regulatory problems associated with radioactive ionization ...
C, Wu   +3 more
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Ion Mobility-Mass Spectrometry

2020
This book focuses on ion mobility-mass spectrometry (IM-MS) and informatics approaches to improve traditional analysis of molecules by providing fundamentals and protocols for exploiting the potential of state-of-the-art IM-MS technology for the most common analytical applications.
Paglia, G, Astarita, G
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Tandem trapped ion mobility spectrometry

The Analyst, 2018
Design, characteristics, and application of tandem trapped ion mobility spectrometry (TIMS-TIMS).
Fanny C. Liu   +3 more
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Fundamentals of Trapped Ion Mobility Spectrometry

Journal of the American Society for Mass Spectrometry, 2014
Trapped ion mobility spectrometry (TIMS) is a relatively new gas-phase separation method that has been coupled to quadrupole orthogonal acceleration time-of-flight mass spectrometry. The TIMS analyzer is a segmented rf ion guide wherein ions are mobility-analyzed using an electric field that holds ions stationary against a moving gas, unlike ...
Karsten, Michelmann   +3 more
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