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Ion mobility spectrometry and ion mobility-mass spectrometry in clinical chemistry
Advancements in clinical chemistry have major implications in terms of public health, prompting many clinicians to seek out chemical information to aid in diagnoses and treatments. While mass spectrometry (MS) and hyphenated-MS techniques such as LC-MS or tandem MS/MS have long been the analytical methods of choice for many clinical applications, theseKyle E, Lira +2 more
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Ion Mobility Spectrometry of Heavy Metals
Analytical Chemistry, 2016A simple, fast, and inexpensive method was developed for detecting heavy metals via the ion mobility spectrometry (IMS) in the negative mode. In this method, Cl(-) ion produced by the thermal ionization of NaCl is employed as the dopant or the ionizing reagent to ionize heavy metals.
Vahideh, Ilbeigi +2 more
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2004
Ion mobility spectrometry was developed for the simple and cheap detection and characterization of organic compounds (Cohen and Karasek, 1970; Karasek, 1970; Caroll et al., 1971; Caroll, 1972; Cohen et al., 1972; Cohen and Crowe, 1973; Vora et al., 1987; St. Louis and Hill, 1990; Campbell et al., 1991; Burke, 1992; Eiceman and Karas, 1994; Taylor, 1996;
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Ion mobility spectrometry was developed for the simple and cheap detection and characterization of organic compounds (Cohen and Karasek, 1970; Karasek, 1970; Caroll et al., 1971; Caroll, 1972; Cohen et al., 1972; Cohen and Crowe, 1973; Vora et al., 1987; St. Louis and Hill, 1990; Campbell et al., 1991; Burke, 1992; Eiceman and Karas, 1994; Taylor, 1996;
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Fourier Transform Ion Mobility Spectrometry
Analytical Chemistry, 1985Theorie du fonctionnement d'un spectrometre a deux portes.
F J, Knorr +3 more
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Tandem trapped ion mobility spectrometry
The Analyst, 2018Design, characteristics, and application of tandem trapped ion mobility spectrometry (TIMS-TIMS).
Fanny C. Liu +3 more
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Liquid phase ion mobility spectrometry
The Analyst, 2011A novel analytical method, called Liquid Phase Ion Mobility Spectrometry (LiPIMS) was demonstrated, where aqueous phase analytes were ionized and introduced into non-aqueous liquids, transported by an external electric field from the point of generation to a collection electrode.
Maggie, Tam, Herbert H, Hill
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IR-MALDI ion mobility spectrometry
Analytical and Bioanalytical Chemistry, 2016The novel combination of infrared matrix-assisted laser dispersion and ionization (IR-MALDI) with ion mobility (IM) spectrometry makes it possible to investigate biomolecules in their natural environment, liquid water. As an alternative to an ESI source, the IR-MALDI source was implemented in an in-house-developed ion mobility (IM) spectrometer.
José Villatoro +5 more
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Ion Mobility-Mass Spectrometry of Glycoconjugates
2019Glycoconjugates are diverse biomolecules that are dynamically assembled to regulate and fine-tune numerous cellular processes. Their biosynthesis is nontemplate-driven, achieved stepwise in discrete locations within the cell, giving rise to a range of complex branched structures that pose a significant challenge in structural biology. Mass spectrometry
Weston B, Struwe, David J, Harvey
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Hadamard Transform Ion Mobility Spectrometry
Analytical Chemistry, 2005Traditionally, the spectrum acquired using ion mobility spectrometry (IMS) is an average of multiple experimental cycles. Each cycle is initiated by passing a short burst of ions into a drift tube containing a homogeneous electric field. Prior to starting the subsequent cycle, all ions in the system must arrive at the detector or spectral overlap may ...
Brian H, Clowers +3 more
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Hadamard Transform Ion Mobility Spectrometry
Analytical Chemistry, 2006A detection scheme that makes use of the Hadamard transform has been employed with an atmospheric-pressure ion mobility spectrometer fitted with an electrospray ionization source. The Hadamard transform was implemented through the use of a linear-feedback shift register to produce a pseudorandom sequence of 1023 points.
Andrew W, Szumlas +2 more
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