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THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY‐MASS SPECTROMETRY
Mass Spectrometry Reviews, 2020Studies of large proteins, protein complexes, and membrane protein complexes pose new challenges, most notably the need for increased ion mobility (IM) and mass spectrometry (MS) resolution. This review covers evolutionary developments in IM‐MS in the authors' and key collaborators' laboratories with specific focus on developments that enhance the ...
Jacob W, McCabe +6 more
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Thin Layer Chromatography-Ion Mobility Spectrometry (TLC-IMS)
Analytical Chemistry, 2014Ion mobility spectrometry (IMS) is a fast and sensitive analytical method which operates at the atmospheric pressure. To enhance the capability of IMS for the analysis of mixtures, it is often used with preseparation techniques, such as GC or HPLC. Here, we report for the first time the coupling of the thin-layer chromatography and IMS.
Vahideh, Ilbeigi, Mahmoud, Tabrizchi
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Journal of the American Society for Mass Spectrometry, 2020
In contrast to classical ion mobility spectrometers (IMS) operating at ambient pressure, the high kinetic energy ion mobility spectrometer (HiKE-IMS) is operated at reduced pressures between 10-40 mbar. In HiKE-IMS, ions are generated in a reaction region before they are separated in a drift region.
Maria Allers +7 more
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In contrast to classical ion mobility spectrometers (IMS) operating at ambient pressure, the high kinetic energy ion mobility spectrometer (HiKE-IMS) is operated at reduced pressures between 10-40 mbar. In HiKE-IMS, ions are generated in a reaction region before they are separated in a drift region.
Maria Allers +7 more
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Opioid Cutting Agents for Use as Internal Standards in Ion Mobility Spectrometry (IMS)
Talanta, 2023Opioids have become a serious public health concern over the last decade. These compounds are commonly found mixed, or cut, with safer compounds to make the opioids appear unadulterated while also enhancing the psychoactive effect on the user. Commercial benchtop and handheld IMS devices are capable of detection but published reduced ion mobility (K0 ...
Charles D, Smith, Braden C, Giordano
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Analysis of explosives using electrospray ionization/ion mobility spectrometry (ESI/IMS)
Talanta, 2000The analysis of explosives with ion mobility spectrometry (IMS) directly from aqueous solutions was shown for the first time using an electrospray ionization technique. The IMS was operated in the negative mode at 250 degrees C and coupled with a quadrupole mass spectrometer to identify the observed IMS peaks.
G R, Asbury, J, Klasmeier, H H, Hill
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A review of recent, unconventional applications of ion mobility spectrometry (IMS)
Analytica Chimica Acta, 2011The applications of ion mobility spectrometry (IMS) have grown exponentially beyond its uses for explosive, illicit drug and chemical warfare agent monitoring in recent years. Instrumental developments including new drift tube materials and ionization sources have enabled the manufacturing of more sophisticated and affordable IMS equipment for the ...
Sergio, Armenta +2 more
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Analytical Chemistry, 2015
A prototype is introduced based on the transversal modulation ion mobility spectrometry (TMIMS) technique, which provides a continuous output of mobility-selected ions, greatly easing the synchronization between different analyzing stages. In the new architecture, two stages of filtration are used to drastically reduce the background produced by one ...
G, Vidal-de-Miguel +3 more
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A prototype is introduced based on the transversal modulation ion mobility spectrometry (TMIMS) technique, which provides a continuous output of mobility-selected ions, greatly easing the synchronization between different analyzing stages. In the new architecture, two stages of filtration are used to drastically reduce the background produced by one ...
G, Vidal-de-Miguel +3 more
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Detection of designer drugs in human hair by ion mobility spectrometry (IMS)
Forensic Science International, 1998Since its inception in the early 1970s under the name plasma chromatography, ion mobility spectrometry (IMS) has undergone great changes. It is now utilized more and more in forensic science laboratories where it is used to detect explosives and environmental pollutants [1-4] as well as its use in detecting drugs of abuse [5-8].
T, Keller +5 more
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Analytical Chemistry, 2012
The analysis of ions according to their mobility is a technique that is attracting increasing interest. The new technology presented here, which we have termed Transversal Modulation Ion Mobility Spectrometry (TM-IMS), utilizes only electric fields, operates at atmospheric pressure, produces a continuous output of mobility selected ions (according to ...
G, Vidal-de-Miguel, M, Macía, J, Cuevas
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The analysis of ions according to their mobility is a technique that is attracting increasing interest. The new technology presented here, which we have termed Transversal Modulation Ion Mobility Spectrometry (TM-IMS), utilizes only electric fields, operates at atmospheric pressure, produces a continuous output of mobility selected ions (according to ...
G, Vidal-de-Miguel, M, Macía, J, Cuevas
openaire +2 more sources