Results 41 to 50 of about 214,764 (339)

Oxygen Donor Stabilized Alkaline Earth Metal Iodides

open access: yesCHIMIA, 2003
Alkaline earth metal iodides show ionic behavior in water, but their bonding situation is not that clear in less polar solvents. The alkaline earth metal iodide adducts, i.e. [MI2(thf)5](M = Sr and Ba), [CaI2(L)4] (L = thf, H2O), [Ba(OH)I(H2O)4]
Katharina M. Fromm
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

A brief review for fluorinated carbon: synthesis, properties and applications

open access: yesNanotechnology Reviews, 2019
Fluorinated carbon (CFx), a thriving member of the carbonaceous derivative, possesses various excellent properties of chemically stable, tunable bandgap, good thermal conductivity and stability, and super-hydrophobic due to its unique structures and ...
Liu Yifan   +8 more
doaj   +1 more source

Multiple representations in web-based learning of chemistry concepts [PDF]

open access: yes, 2003
A new chemistry curriculum for secondary schools is currently under construction in the Netherlands, in which chemical knowledge will be embedded in contexts that show applications of chemistry in the society. Several research groups develop such modules
Dijkstra, Sanne   +2 more
core   +1 more source

Electronic, magnetic properties and correlation effects in the layered quaternary iron oxyselenide Na2Fe2Se2O from first principles

open access: yes, 2012
By means of the first-principle calculations, we have investigated electronic, magnetic properties and correlation effects for the newly discovered layered oxyselenide Na2Fe2Se2O.
A.L. Ivanovskii   +19 more
core   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Hydrogen bonding in ionic liquids probed by linear and nonlinear vibrational spectroscopy

open access: yesNew Journal of Physics, 2012
Three imidazolium-based ionic liquids of the type [C _n mim][NTf _2 ] with different alkyl chain lengths ( n  = 1, 2 and 8) at the first position of the imidazolium ring were studied applying infrared, linear Raman and multiplex coherent anti-Stokes ...
C Roth   +7 more
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Chemistry Games in the Classroom: A Pilot Study [PDF]

open access: yesJournal of Research in Science, Mathematics and Technology Education, 2018
In this study a game-based learning approach was introduced among students and teachers. Several chemistry games and a survey method were used as a tool to obtain insight into students’ knowledge about ionic bonding, to learn about the students’ and ...
Marina Stojanovska, Blaga Velevska
doaj   +1 more source

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