Results 91 to 100 of about 342,437 (282)

The Escape of Ionizing Photons from the Galaxy

, 1998
The Magellanic Stream and several high velocity clouds have now been detected in optical line emission. The observed emission measures and kinematics are most plausibly explained by photoionization due to hot, young stars in the Galactic disk. The highly
Giallongo E., J. Bland-Hawthorn, Mezger P., Moore B., Philip R. Maloney   +4 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Spatial methods for event reconstruction in CLEAN

, 2003
In CLEAN (Cryogenic Low Energy Astrophysics with Noble gases), a proposed neutrino and dark matter detector, background discrimination is possible if one can determine the location of an ionizing radiation event with high accuracy.
Bard, Beacom, Bruyant, Daniel N. McKinsey, Fukuda, Fukuda, Gao, Gay, Horowitz, Kahaner, Kevin J. Coakley, Krol, Lehmann, McKinsey, Nelson, Peplow, Shepp, Vardi, Wood, Yang   +19 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Dosimeter for high levels of absorbed radiation Patent [PDF]

, 1969
Development of dosimeter for measuring absorbed dose of high energy ionizing ...
Bell, V. L., Jr., Pezdirtz, G. F.
core   +1 more source

Escape fraction of ionizing photons from high-redshift galaxies in cosmological SPH simulations

, 2010
Combing the three-dimensional radiative transfer (RT) calculation and cosmological SPH simulations, we study the escape fraction of ionizing photons (f_esc) of high-redshift galaxies at z=3-6.
Adelberger, Agertz, Becker, Bolton, Bouwens, Choi, Choi, Choi, Ciardi, Davé, Dove, Dove, Draine, Draine, Dunkley, Fan, Fan, Fioc, Fujita, Giallongo, Gnedin, Gnedin, Gnedin, Haardt, Hasegawa, Hidenobu Yajima, Iliev, Iliev, Inoue, Inoue, Iwata, Jun-Hwan Choi, Kentaro Nagamine, Komatsu, Madau, Madau, Mathis, Mori, Murray, Nagamine, Nagamine, Nakamoto, Okamoto, Osterbrock, Page, Pawlik, Razoumov, Razoumov, Ricotti, Sales, Salpeter, Shapley, Sokasian, Springel, Springel, Springel, Springel, Steidel, Susa, Susa, Umemura, Wise, Wood, Yajima   +63 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The escape fraction of ionizing photons from high redshift galaxies

, 2008
The fraction of ionizing photons which escape their host galaxy and so are able to ionize hydrogen in the inter-galactic medium (IGM) is a critical parameter in studies of the reionization era and early galaxy formation.
Barkana, Bergvall, Deharveng, Inoue, J. Stuart B. Wyithe, Jhan A. Srbinovsky, Scalo   +6 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Primordial Galaxy Formation and IGM Reionization

, 2001
In this talk I will present a model for primordial galaxy formation. In particular, I will review the feedback effects that regulate the process: (i) radiative (i.e. ionizing and H_2-photodissociating photons) and (ii) stellar (i.e.
Ciardi, Benedetta
core   +1 more source