Results 51 to 60 of about 342,437 (282)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Evaluation of the Protective Role of Vitamin C on the Metabolic and Enzymatic Activities of the Liver in the Male Rats After Exposure to 2.45 GHz Of Wi-Fi Routers

Journal of Biomedical Physics and Engineering, 2016
Background: The use of devices emitted microwave radiation such as mobile phones, wireless fidelity (Wi-Fi) routers, etc. is increased rapidly. It has caused a great concern; the researchers should identify its effects on people’s health.
Shekoohi-Shooli F., Mortazavi S. M. J., Shojaei-fard M. B., Nematollahi S., Tayebi M.   +4 more
doaj  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Quadrupole ionization gage measures ultrahigh vacuum [PDF]

, 1970
Quadrupole system, energized with a 200 MHz electric field, restrains ionizing electrons within the center of the ionization gage. Oscillatory trajectory of the electrons increases the probability of ionizing the gas molecules, lowers background X-ray ...
Schwarz, H. J.
core   +1 more source

The Ionizing Efficiency of the First Stars [PDF]

, 2003
We investigate whether a single population of first stars could have influenced both the metal enrichment and reionization of the high-redshift intergalactic medium (IGM), by calculating the generated ionizing radiation per unit metal yield as a function
Truran, James W., Venkatesan, Aparna
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Exploring Non-Genetic Factors in Cancer Resistance among Ramsar Residents: From Medical Geology to the Role of Diet: A Review [PDF]

International Journal of Nutrition Sciences
Ramsar in northern Iran provides a unique natural setting to investigate the biological effects of exposure to chronic radiation and the potential adaptive mechanisms. It is owing to its exceptional high concentrations of radium in sedimentary rocks, hot
Hassan Bahrami, Pouya Zohdparast, Hassan Vafapour, AmirAli Fallah, Seyed Mohammad Javad Mortazavi, Fateme Zaker, Maryam Arshadi, Alireza Mortazavi, Seyed Jalil Masoumi   +8 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Short–Term Exposure to Electromagnetic Fields Generated by Mobile Phone Jammers Decreases the Fasting Blood Sugar in Adult Male Rats

Journal of Biomedical Physics and Engineering, 2016
Background: Substantial evidence indicates that exposure to electromagnetic fields (EMF) above certain levels can affect human health through triggering some biological responses.
Shekoohi Shooli F., Mortazavi S. A. R., Jarideh S., Nematollahii S, Yousefi F., Haghani M., Mortazavi S. M. J., Shojaei-fard M. B.   +7 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source