Results 81 to 90 of about 342,437 (282)

Cosmic Variance In the Transparency of the Intergalactic Medium After Reionization

, 2006
Following the completion of cosmic reionization, the mean-free-path of ionizing photons was set by a population of Ly-limit absorbers. As the mean-free-path steadily grew, the intensity of the ionizing background also grew, thus lowering the residual ...
Abraham Loeb, Baugh C. M., Bolton J. S., J. Stuart B. Wyithe   +3 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Radiation Driven Implosion and Triggered Star Formation [PDF]

, 2010
We present simulations of initially stable isothermal clouds exposed to ionizing radiation from a discrete external source, and identify the conditions that lead to radiatively driven implosion and star formation.
Anthony P. Whitworth, Bate, Bate, Bonnor, Chandrasekhar, David A. Hubber, Ebert, Elmegreen, Gritschneder, Górski, Ikeda, Indebetouw, Kahn, Krumholz, Lefloch, Lefloch, Lefloch, Miao, Mizuta, Mizuta, Osterbrock, Richard Wünsch, Smith, Stefanie Walch, Sugitani, Sugitani, Sugitani, Thomas G. Bisbas, Walborn   +28 more
core   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Critical Role of Radiation Protection in Modern Life [PDF]

Journal of Biomedical Physics and Engineering
The Critical Role of Radiation Protection in Modern LifeThe Critical Role of Radiation Protection in Modern LifeThe Critical Role of Radiation Protection in Modern LifeThe Critical Role of Radiation Protection in Modern LifeThe Critical Role of Radiation
James Welsh, Seyed Mohammad Javad Mortazavi, Lembit Sihver   +2 more
doaj   +1 more source

Direct Observations of the Ionizing Star in the UC HII Region G29.96-0.02: A Strong Constraint on the Stellar Birth Line for Massive Stars [PDF]

, 1997
We have observed the ultracompact HII region G29.96-0.02 in the near infrared J, H, and K bands and in the Br-gamma line. By comparison with radio observations, we determine that the extinction to the nebula is AK = 2.14 with a 3 sigma uncertainty of 0 ...
Alan M. Watson, Alison L. Coil, Bernasconi P. A., Cabrit S., Casali M. M., Cesaroni R., Chini R., Claussen M. J., Debra S. Shepherd, Doherty R. M., Downes D., Dyson J. E., Ed Churchwell, Harvey P. M., Hofner P., Hummer D. G., Hunter T. R., Koornneef J., Lizano S., Meynet G., Mooney T., Najarro F., Peter Hofner, Redman M. P., Thejll P., Williams R. J. R.   +25 more
core   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Milky Way Star Forming Complexes and the Turbulent Motion of the Galaxy's Molecular Gas

, 2012
We analyze Spitzer GLIMPSE, MSX, and WMAP images of the Milky Way to identify 8 micron and free-free sources in the Galaxy. Seventy-two of the eighty-eight WMAP sources have coverage in the GLIMPSE and MSX surveys suitable for identifying massive star ...
Lee, E. J., Murray, N., Rahman, M.
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source