Investigating the interactions and conformations of metalloproteins by means of mass spectrometry [PDF]
The use of mass spectrometry for the study of proteins and their non-covalent interactions has expanded rapidly since the introduction of ionisation techniques capable of transferring intact complexes into the gas phase.
Kondrat, Frances D. L.
core
Fragment Coverage: Unified Visualization and Quantitative Assessment of MS/MS Fragmentation Supports Metabolite Identification in Macromolecule Drug Metabolism Studies. [PDF]
Cifuentes P +3 more
europepmc +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Sensitivity Enhancement by Dual Deflection Electrodes in an Electrospray Ionization Source. [PDF]
Date M +4 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Optical Spectroscopy and Crystal Field Analysis of Ni<sup>2+</sup> Centres in Lithium Tetraborate Glass. [PDF]
Kindrat I +3 more
europepmc +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Investigation of Trpa1 and Trpc1 Immunreactivities in Colon Adenocarcinomas
Ahmet Bozdag,1 Tuncay Kuloglu,2 Gokhan Artas,3 Suleyman Aydin4 1Department of General Surgery, School of Medicine, Firat University, Elazig, Turkey; 2Department of Histology and Embryology, School of Medicine, Firat University, Elazig, Turkey ...
Bozdag A, Kuloglu T, Artas G, Aydin S
doaj
Gating Modes in Ion Mobility-Mass Spectrometry: Principles, Advances, and Coupling With Mass Analyzers. [PDF]
Li T, Xiong S, Jiang T, Xu W.
europepmc +1 more source
MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source

