Results 61 to 70 of about 201 (112)

Qualitative and quantitative tests for iothalamic acid

open access: closedJournal of Pharmaceutical Sciences, 1963
Donald E. Cadwallader
openaire   +2 more sources

[A method for the simultaneous determination of iothalamic acid and creatinine clearance by coupled-column liquid chromatography].

open access: closedRinsho byori. The Japanese journal of clinical pathology, 1992
[125I]iothalamic acid clearance is used for the estimation of glomerular filtration rate. Therefore, we developed a coupled-column liquid chromatography for the simultaneous determination of iothalamic acid and creatinine in human serum and urine samples to calculate their clearance.
T, Seki   +5 more
openaire   +2 more sources

Absorption of iothalamate after oral administration and absorption enhancement by amino acids in dogs and rats

Biopharmaceutics & Drug Disposition, 1986
AbstractThe oral absorption of iothalamate and the effect of amino acids on its absorption were studied in 6 dogs and 6 rats using a simple HPLC assay. The results showed that iothalamate was absorbed in dogs, averaging 9·9, 8·5, and 10·0 per cent following the administration of 40 and 100mg kg−1 of iothalamic acid capsules and 50mg kg−1 of sodium ...
T, Prueksaritanont   +3 more
openaire   +2 more sources

Simultaneous determination of p-aminohippuric acid, acetyl-p-aminohippuric acid and iothalamate in human plasma and urine by high-performance liquid chromatography

Journal of Chromatography B: Biomedical Sciences and Applications, 1998
A sensitive and specific high-performance liquid chromatographic assay was developed for the simultaneous determination of p-aminohippuric acid (PAH), acetyl-p-aminohippuric acid (aPAH), and iothalamate in human plasma and urine. Plasma samples were prepared by protein precipitation with acetonitrile followed by evaporation, reconstitution in mobile ...
T C, Dowling, R F, Frye, M A, Zemaitis
openaire   +2 more sources

Simple and micro high-performance liquid chromatographic method for simultaneous determination of p-aminohippuric acid and iothalamate in biological fluids

Journal of Chromatography B: Biomedical Sciences and Applications, 1984
A simple, rapid and micro high-performance liquid chromatographic method was developed for separate or simultaneous determination of p-aminohippuric acid and iothalamate in plasma and urine using p-aminobenzoic acid as an internal standard. The method involved deproteinizing samples with two volumes of acetonitrile followed by injection of 5 ...
T, Prueksaritanont   +2 more
openaire   +2 more sources

Renal Scanning 99mTc Diethylene-Triamine Pentaacetic Acid Glomerular Filtration Rate (GFR) Determination Compared With Iothalamate Clearance GFR in Diabetics

American Journal of Kidney Diseases, 1992
Traditionally, creatinine clearance is used as an estimation of the glomerular filtration rate (GFR) because of its relative ease and low cost. Errors in collection limit its usefulness. Estimation of GFR using 99m Tc diethylene-triamine pentaacetic acid (Tc-DTPA) by direct scintigraphic determination of fractional radionuclide accumulation within ...
Roger A. Rodby   +3 more
openaire   +1 more source

High-performance liquid chromatographic determination of p-aminohippuric acid and iothalamate in human serum and urine: comparison of two sample preparation methods

Journal of Chromatography B: Biomedical Sciences and Applications, 2000
A high-performance liquid chromatography method applied to determine p-aminohippuric acid (PAH) and iothalamate (IOT) in serum and urine samples of patients was evaluated according to recovery, reproducibility and linearity utilizing narrow-bore columns.
T, Kos   +5 more
openaire   +2 more sources

Simple HPLC–UV method for determination of iohexol, iothalamate, p-aminohippuric acid and n-acetyl-p-aminohippuric acid in human plasma and urine with ERPF, GFR and ERPF/GFR ratio determination using colorimetric analysis

Journal of Chromatography B, 2005
A simple high-performance liquid chromatographic (HPLC) method was developed for the simultaneous determination of iohexol, iothalamate, p-aminohippuric acid (PAH) and n-acetyl-p-aminohippuric acid (n-acetyl-PAH) in human plasma and urine. A C(18) column at a flow rate of 1 ml/min with an aqueous mobile phase of trifluoroacetic acid (0.1% TFA in ...
Don, Farthing   +7 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy