Results 121 to 130 of about 186,246 (311)
Advanced Science, EarlyView.We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel +16 more
wiley +1 more source
, 2008 Field observations and three-dimensional (3D) radiative transfer (RT) simulations of the actinic flux density show strongly pronounced local variations in the presence of inhomogeneous cloud fields which depend on the spatial distribution of the clouds ...
Kniffka, Anke, Trautmann, Thomas
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Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq
Advanced Science, EarlyView.Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su +10 more
wiley +1 more source
Al-AuladThis research aims to determine the difference in the average increase in students' cognitive learning outcomes in science subjects using the Science, Environment, Technology and Society (SETS) approach and the conventional approach. This research uses a
Hilman Mangkuwibawa +2 more
doaj +1 more source
PROFIL LULUSAN CALON GURU IPA MELALUI PENGINTEGRASIAN KEARIFAN LOKAL DALAM PERKULIAHAN
, 2014 Profil lulusan calon guru IPA ditentukan sesuai kebutuhan dan perkembangan ilmu pengetahun dan teknologi. Kompetensi utama lulusan yang telah ditetapkan diantaranya memiliki kemampuan menyusun bahan ajar IPA, silabus, rencana pelaksanaan pembelajaran dan
-, Taufiq -; Program Studi Pendidikan IPA Jurusan IPA Terpadu FMIPA Unnes +1 more
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β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Potensi Kearifan Lokal dalam Pembelajaran IPA di SMP
, 2015 Masyarakat telah mengembangkan sistem pengetahuan dan teknologi yang asli sebagai suatu kearifan lokal (indigenous or local knowledge), mencakup berbagai macam cara untuk mengatasi permasalahan kehidupan, seperti pengolahan sumber daya lingkungan ...
Parmin, Parmin; Prodi Pendidikan IPA Jurusan IPA Terpadu FMIPA UNNES
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