Results 41 to 50 of about 3,563 (216)
Advanced Science, EarlyView.Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes +15 more
wiley +1 more source
Molecules, 2020 To date, Mycobacterium tuberculosis (Mtb) remains the world’s greatest infectious killer. The rise of multidrug-resistant strains stresses the need to identify new therapeutic targets to fight the epidemic.
Laure Tonini +6 more
doaj +1 more source
Step‐by‐Step Technique for Platelet‐Rich Plasma Gel Preparation and Use in Knee Osteoarthritis
Arthroscopy Techniques, EarlyView.Abstract Knee osteoarthritis (OA) remains a leading cause of pain and disability worldwide, and current injectable options such as corticosteroids and hyaluronic acid often provide limited or short‐term benefits. Orthobiologic therapies, particularly platelet‐rich plasma (PRP), have gained attention for their regenerative and anti‐inflammatory ...
Diego Ariel de Lima +6 more
wiley +1 more source
AgronomyInvestigating the genetic diversity and population structure of wheat germplasm is crucial for understanding the underlying variability essential for breeding programs and germplasm preservation.
Fatih Demirel +8 more
doaj +1 more source
Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy
Molecules, 2020 Protein degradation is tightly regulated inside cells because of its utmost importance for protein homeostasis (proteostasis). The two major intracellular proteolytic pathways are the ubiquitin-proteasome and the autophagy-lysosome systems which ensure ...
Grégoire Quinet +3 more
doaj +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Arboreta bridge people and nature while conserving tree biodiversity, supporting climate resilience, and advancing environmental education. This study maps over a century of available and indexed arboretum research, uncovering trends, knowledge gaps, and opportunities for collaboration.
Catarina Patoilo Teixeira +1 more
wiley +1 more source
Scientific Reports, 2021 Owing to their role in activating enzymes essential for bacterial viability and pathogenicity, phosphopantetheinyl transferases represent novel and attractive drug targets. In this work, we examined the inhibitory effect of the aminido-urea 8918 compound
Coralie Carivenc +10 more
doaj +1 more source
Complex Regulation of RETINOBLASTOMA‐RELATED's Interactions With E2Fs via Phosphorylation
Plant, Cell &Environment, EarlyView.ABSTRACT Arabidopsis RETINOBLASTOMA‐RELATED (RBR) regulates cell proliferation by interacting with E2F transcription factors and DIMERISATION PARTNER, RB‐LIKE, E2F AND MULTI‐VULVAL CLASS B COMPLEX (DREAM) components. Although CDK‐CYCD phosphorylation is believed to affect RBR's E2F‐binding capacity, the precise phosphorylation events inhibiting RBR's ...
Aladár Pettkó‐Szandtner +10 more
wiley +1 more source
Evaluating Attendance Methods on IPB-Mobile for Student Application: A Case Study in IPB University
Letters in Information Technology Education (LITE), 2023 Currently, education is a crucial aspect of life. Technology has led to adaptations across various sectors, including higher education. One of these adaptations is the emergence of online attendance recording systems. IPB University has responded seriously to this by launching the IPB-Mobile for Student for Student app, which is equipped with a mobile ...
Najla Amelia Putri +7 more
openaire +1 more source
Deciphering sulfoglycolipids of Mycobacterium tuberculosis[S]
Journal of Lipid Research, 2011 For 4 decades, in vivo and in vitro studies have suggested that sulfoglycolipids (SGLs) play a role in the virulence or pathogenesis of the tubercle bacilli. However, the SGL structure and biosynthesis pathway remain only partially elucidated.
Emilie Layre +7 more
doaj +1 more source