Results 91 to 100 of about 287,226 (291)

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Comparison Of Lower Extremity Bilateral and Ipsilateral Strength Asymmetry in Male and Female Soccer Players

Research in Sport Education and Sciences
The aim of this study was to compare bilateral and ipsilateral lower extremity strength asymmetry in male and female soccer players. This study was conducted with cross-sectional research model. A total of 74 soccer players, 36 women and 38 men, who play
Gizem Akarsu Taşman, Erkan Güven, Nasuh Evrim Acar   +2 more
doaj   +1 more source

Fluctuations in instantaneous frequency predict alpha amplitude during visual perception. [PDF]

, 2017
Rhythmic neural activity in the alpha band (8-13 Hz) is thought to have an important role in the selective processing of visual information. Typically, modulations in alpha amplitude and instantaneous frequency are thought to reflect independent ...
Itthipuripat, Sirawaj, Nelli, Stephanie, Serences, John T, Srinivasan, Ramesh   +3 more
core   +3 more sources

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Sensory sensitivity as a link between concussive traumatic brain injury and PTSD. [PDF]

, 2019
Traumatic brain injury (TBI) is one of the most common injuries to military personnel, a population often exposed to stressful stimuli and emotional trauma.
Fanselow, Michael S, Giza, Christopher C, Hoffman, Ann N, Hovda, David A, Lam, Jamie   +4 more
core   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Prismatic adaptation modulates oscillatory EEG correlates of motor preparation but not visual attention in healthy participants [PDF]

, 2017
Prismatic adaption (PA) has been proposed as a tool to induce neural plasticity and is used to help neglect rehabilitation. It leads to a recalibration of visuo-motor coordination during pointing as well as to after-effects on a number of sensorimotor ...
Bracco, Martina, Oliveri, Massimiliano, Thut, Gregor, Veniero, Domenica   +3 more
core   +4 more sources

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

Advanced Science, EarlyView.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao, Hongli Zhang, Yating Yang, Wei‐Dong Chen, Yan‐Dong Wang   +4 more
wiley   +1 more source

Symptomatic Ipsilateral Limb Twisting Due to Extensive Rotational Re-orientation of the C3 Excluder

EJVES Short Reports, 2019
Introduction: Since the introduction of the Gore C3 device, which allows level re-positioning and contralateral gate cannulation, there have been very few reported complications due to excessive readjustment attempts.
Osamu Sakai, Katsuhiko Oka, Tomoya Inoue, Keiichi Kanda, Hitoshi Yaku   +4 more
doaj   +1 more source