Results 71 to 80 of about 287,226 (291)

Challenges in managing ipsilateral femoral neck and shaft fracture at Mission Hospital

CHRISMED Journal of Health and Research, 2016
Rarity of ipsilateral femoral neck and shaft fracture qualifies it as a difficult fracture to diagnose as well as treat. No ideal treatment option has been defined, and no ideal implant has been assigned for the management of such fractures.
Deeptiman James
doaj   +1 more source

Prepontine non-giant neurons drive flexible escape behavior in zebrafish [PDF]

, 2019
Many species execute ballistic escape reactions to avoid imminent danger. Despite fast reaction times, responses are often highly regulated, reflecting a trade-off between costly motor actions and perceived threat level.
Bergeron, S., Briggman, K., Burgess, H., Marquart, G., Tabor, K.   +4 more
core   +2 more sources

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Four collateral circulation pathways were observed after common carotid artery occlusion

BMC Neurology, 2019
Background Common carotid artery (CCA) occlusion (CCAO) is a rare condition. Owing to collateral circulation, ipsilateral internal carotid artery (ICA) and external carotid artery (ECA) are often patent.
Jianan Wang, Chengrong Zheng, Bei Hou, Aihua Huang, Xiongwei Zhang, Bin Du   +5 more
doaj   +1 more source

The spino-bulbar-cerebellar pathway: organization and neurochemical properties of spinal cells that project to the lateral reticular nucleus in the rat [PDF]

, 2015
In addition to classical spinocerebellar pathways, the cerebellum receives information from the spinal cord indirectly via spino-bulbar-cerebellar systems. One of the structures in this pathway is the lateral reticular nucleus (LRt).
Huma, Zilli, Maxwell, David J.
core   +2 more sources

Ipsilateral Maxillo-Mandibular Ossifying Fibroma [PDF]

Journal of Maxillofacial and Oral Surgery, 2012
Ossifying fibroma is a benign fibro-osseous lesion which occurs at various locations in maxillofacial region. A synchronous presentation of this lesion in both, the maxilla and the mandible is a rare occurrence. The present article reports a case of ossifying fibroma in a 45-year-old woman who manifested lesions in the right maxilla and mandible.
Amit, Tyagi, Sunil, Chaudhary, Vineet, Gupta   +2 more
openaire   +2 more sources

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Impact of Extended Dosing Intervals and Ipsilateral Versus Contralateral Boosting on mRNA Vaccine Immunogenicity in Mice

Vaccines
Background: Although mRNA vaccines have the potential to be developed and deployed rapidly to combat infectious diseases, the ideal method of administration and boosting schedule strategy for generating optimal immunogenicity is an area of active ...
Bin Lu, Omkar Chaudhary, Balaji Banoth, Janhavi Nadkarni, Wei Zong, Emilie Mausser, Hillary Danz, Mona Motwani, Sophie Ruiz, Donghui Zhang, Gopinath Nageshwaran, Bachra Rokbi, William Warren, Frank DeRosa, Sudha Chivukula   +14 more
doaj   +1 more source

Risk of contralateral lower limb amputation and death after initial lower limb amputation – a population-based study

Heliyon, 2018
Background: Lower limb amputation (LLA) is a complication of lower limb atherosclerosis, infection and tissue gangrene. Following ipsilateral LLA, the risk of major amputation of the contralateral limb or of death is unknown. The aim of this study was to
K. Huseynova, R. Sutradhar, G.L. Booth, A. Huang, J.G. Ray   +4 more
doaj   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source