Results 41 to 50 of about 5,872,441 (286)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Development of Genistein Synthesis for Use as a Certified Reference Material
Разработка и регистрация лекарственных средств, 2021 Introduction. The use of certified reference materials (CRMs) ensures metrological traceability and comparability of analysis results performed in different laboratories, by different analysts, at different times.
A. A. Zhigalina +3 more
doaj +1 more source
Effect of Catalyst in Volume Percent Yield Biodiesel From Stearin by Transesterification Process [PDF]
, 2011 Use of fuel oil is increasingly high, but the problem is not in line with the production of fuel oil which is increasingly lower, so to anticipate and meet the fuel needs of the growing diesel engine, it requires a search and research on alternative ...
Erlinawati, M.T, Ir
core +1 more source
Physics of the Non-Abelian Coulomb Phase: Insights from Pad\'e Approximants [PDF]
, 2017 We consider a vectorial, asymptotically free SU($N_c$) gauge theory with $N_f$ fermions in a representation $R$ having an infrared (IR) fixed point.
Ryttov, Thomas A., Shrock, Robert
core +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Attenuation of Infrared Radiation When Passing Through a Water Curtain [PDF]
, 2017 This article focuses on the interaction of infrared (IR) radiation with water droplets. The main objective of the article is the production of water mist in order of evaluation the reduction in intensity of IR radiation. In the experiments described in
Balner, Dalibor +2 more
core +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
ANALYSIS OF STRUCTURAL FEATURES OF THE KETO-KETAL ISOMERS OF WARFARIN BY SPECTRAL METHODS
Разработка и регистрация лекарственных средств, 2019 As a result of the studies was shown that the relative ratios of isomers by integration in DMSO-d6: (S, R)-warfarin – (S, S)-warfarin – open chain warfarin are 70%: 28%: 2%; in СDCl3 are 45%: 40%: 15%.
A. Z. Abyshev +2 more
doaj
Lectin-induced alterations of the interaction of insulin and insulin-like growth factor 1 receptors with their ligands [PDF]
Journal of the Serbian Chemical Society, 2008 In order to study whether the carbohydrate moieties of the human placental IGF-I receptor (IGF1R), IGF-II receptor (IGF2R) and insulin receptors (IRs) play a role in ligand binding, solubilised cell membrane preparations were incubated with 125I-labelled
Masnikosa Romana +2 more
doaj +1 more source