Results 41 to 50 of about 340,794 (262)
Operationalizing the knowledge space: theory, methods and insights for Smart Specialisation
Regional Studies, Regional Science, 2020 Focusing explicitly on the regional dimensions of technological change, this paper examines the technological evolution of Irish NUTS-3 regions. Employing an index of average relatedness, it is shown that over an extended 25-year period (1981–2005) that ...
Adam Whittle
doaj +1 more source
Trans-gendering the Irish Na(rra)tion: Neil Jordan’s Breakfast on Pluto [PDF]
Estudios Irlandeses, 2022 Occupying a relegated position as it does in Neil Jordan’s filmography, it is my contention that Breakfast on Pluto is one of his most transgressive films.
E. Guillermo Iglesias-Díaz
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Irish audiences and news information from official sources during Covid-19
Administration, 2022 Audiences exist in highly personalised, high-choice media environments built on a hybrid of established traditional brands and informal digital networks.
Wheatley Dawn
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Change, Stasis and Celtic Tiger Ireland in the Short Stories of There Are Little Kingdoms (2007) by Kevin Barry [PDF]
Estudios Irlandeses, 2022 This essay focuses on Irish writer Kevin Barry’s first collection of short stories, There Are Little Kingdoms (2007). The Ireland depicted in this work is the Ireland of the new millennium – a territory facing the transformations of Celtic Tiger ...
Madalina Armie
doaj
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The National Spatial Strategy: Lessons for implementing a National Planning Framework
Administration, 2016 The Irish Government is in the process of developing a National Planning Framework (NPF). This will replace the National Spatial Strategy for Ireland 2002-2020 (NSS).
Ó’Riordáin Sean, Egeraat Chris van
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Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Tobacco Prevention and Cessation, 2023 Introduction Tobacco-Free Ireland (TFI) policy sets an ambitious tobacco endgame goal of reducing smoking prevalence to less than 5% by 2025. 1 However, Irish public opinion on tobacco endgame, a key potential policy lever, 2 is largely uncharted. This
Ellen Cosgrave +5 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source