Results 91 to 100 of about 818,391 (312)

All-Ireland Traveller Health Study

open access: yes, 2010
Summary of Findings (PDF 9.4mb) Alongside the executive summary above, this report is further broken into 3 technical reports and an appendix, which are available below.
Department of Health (Ireland)
core   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao   +12 more
wiley   +1 more source

Get Ireland Active: The National Guidelines on Physical Activity for Ireland

open access: yes, 2009
The National Guidelines on Physical Activity for Ireland Click here to download PDF 3.1mb Consumer Leaflet PDF 932kb Fact Sheet for Adults PDF 667kb Fact Sheet for Parents and Guardians PDF 574kb Foldout Executive Summary PDF ...
Department of Health (Ireland)
core   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

open access: yesAdvanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias   +23 more
wiley   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

open access: yesAdvanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin   +9 more
wiley   +1 more source

Biobanking in Ireland: Moving Forward. Irish Health Research Forum Recommendations and Event Report [PDF]

open access: yes
This report presents the proceedings of the Irish Health Research Forum on November 16th 2023, focusing on progressing biobanking in Ireland, and makes key recommendations for moving biobanking forward.Roche Products ...
Health Research Charities Ireland
core  

Giant Direct Magnetoelectric Effect in Nanocomposite CoFe2O4:PVDF‐TrFE Thin Films

open access: yesAdvanced Science, EarlyView.
A novel three‐step grow‐etch‐fill fabrication approach creates structured cobalt ferrite/ferroelectric polymer nanocomposites with high interfacial areas. Driven by efficient strain‐mediated coupling, this crystalline system achieves a giant room‐temperature magnetoelectric coefficient nearly two orders of magnitude higher than other CFO/PVDF‐TrFE thin
Muireann de h‐Óra   +8 more
wiley   +1 more source

Different Schemes, Same City? How lessons from Luas Cross City works are informing the design and implementation of the Luas Finglas and MetroLink Cultural Heritage Strategies

open access: yesInternet Archaeology
Transport Infrastructure Ireland (TII) Archaeology and Heritage operate under a Code of Practice (CoP) for Archaeology (2017) as agreed with the present Minister for Housing, Local Government and Heritage (MHLGH).
Emer Dennehy
doaj   +1 more source

Lessons from abroad: Rebalancing accountability and pedagogy in the Irish social care sector through the use of effective leadership

open access: yesAdministration, 2016
A concern is emerging in Ireland that social care managers and staff are moving too far away from the ‘care’ in social ‘care’ work. In this paper a discussion of the impact of the bureaucratic procedures and regulation within the social work and social ...
Jones Cathy, Smey Carston Catherine
doaj   +1 more source

Home - About - Disclaimer - Privacy