Results 161 to 170 of about 1,664,274 (311)

Cyclo‐Polyproline: Chameleonic All‐Peptide Macrocycles With Induced‐Fit Host‐Guest Recognition

open access: yesAngewandte Chemie, EarlyView.
Macrocycles served as the genesis of supramolecular chemistry, advancing synthetic, separation, and materials fields. Despite their utility, they typically lack synthetic control. This work establishes a robust platform for all‐peptide macrocycles capable of host‐guest complexation and chameleonic behavior.
Camilla Di Girolamo   +9 more
wiley   +2 more sources

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media

open access: yesAnnals of Neurology, EarlyView.
Objective Aqueously diffusible oligomers of the amyloid β‐protein (oAβ) are neurotoxic and play a role in neuronal dysfunction in Alzheimer's disease (AD). Accurate quantification of oAβ in brains and biofluids could be valuable for understanding and monitoring AD.
Yi Ran Xu   +11 more
wiley   +1 more source

Pre‐Diagnostic Plasma Carotenoids, Tocopherols and Retinol Levels, and Risk of Amyotrophic Lateral Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Our goal was to examine whether pre‐diagnostic plasma carotenoids and tocopherols are associated with amyotrophic lateral sclerosis (ALS). Methods A nested case–control study within 4 United States cohorts, where 154 participants with pre‐diagnostic blood‐draw, were diagnosed during follow‐up with amyotrophic lateral sclerosis (ALS). Controls
Éilis J. O'Reilly   +7 more
wiley   +1 more source

Implementation of turbulence models into simulators [PDF]

open access: yes
Simulation of turbulence as it relates to the flight training environment is discussed in general terms. Simulators that put random white noise into the system and simulators that put random motion into the equations of motion are discussed, as are ...
Ireland, Robert L.
core   +1 more source

ECONOMIC INTEGRATION AND HUMAN CAPITAL INVESTMENT [PDF]

open access: yes
In this paper we seek to characterize a market for heterogeneous managers created by heterogeneous firms and the decisions on investment in both sector-specific and firm-specific human capital when those decisions are made prior to the realization of ...
Ireland, Norman, Merzoni, Guido
core  

Functional models from limited data: A parametric and multimodal approach to anatomy and 3D kinematics of feeding in basking sharks (Cetorhinus maximus)

open access: yesThe Anatomical Record, EarlyView.
Abstract Basking sharks, Cetorhinus maximus (Gunnerus, Brugden [Squalus maximus], Det Kongelige Norske Videnskabers Selskabs Skrifter, 1765, vol. 3, pp. 33–49), feed by gaping their mouths and gill slits, greatly reorienting their cranial skeletons to filter food from water.
Tairan Li   +12 more
wiley   +1 more source

Much more than their fangs: Macroscopic anatomy of the brain of Bothrops moojeni Hoge 1966 (Squamata, Serpentes, Viperidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo   +2 more
wiley   +1 more source

RETRACTED: Richards et al. Protein Tyrosine Phosphatase Non-Receptor 11 (<i>PTPN11</i>/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC). <i>Int. J. Mol. Sci.</i> 2023, <i>24</i>, 10545. [PDF]

open access: yesInt J Mol Sci
Richards CE   +15 more
europepmc   +1 more source

Clade‐wide morphological and functional variation of the sauropsid columella

open access: yesThe Anatomical Record, EarlyView.
Abstract The columella (=stapes) is the middle ear bone of reptiles that transmits vibrations from the environment to the inner ear. It has been shown to exhibit extensive interspecific morphological disparity in several clades; however, its morphological variation and associated functional consequences remain poorly described.
John Peacock   +4 more
wiley   +1 more source

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