Results 261 to 270 of about 786,071 (341)

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Windowed Mean Drift Exponentially Weighted Moving Average Control Chart for Monitoring Complex Autocorrelated Processes

open access: yesQuality and Reliability Engineering International, EarlyView.
ABSTRACT In modern manufacturing environments, traditional statistical process control (SPC) methods often struggle with complex, dynamic data patterns, particularly when observations are autocorrelated. Control charts are useful tools used in SPC to detect any significant drift in a process.
Jeanette Maria Louw   +3 more
wiley   +1 more source

Long‐Range Time‐Correlated Single‐Photon Counting Lidar 3D‐Reconstruction From a Moving Ground Vehicle

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Time‐correlated single‐photon counting (TCSPC) lidar enables high‐resolution 3D imaging at kilometer range. While previous works have covered long range TCSPC 3D imaging from either stationary or airborne platforms, this is, to the best of our knowledge, the first attempt that use a moving ground vehicle. Fusing measurements taken at different
Hannes Ovrén   +2 more
wiley   +1 more source

The Molecular Basis of Growth Control in Guanine Crystals

open access: yesSmall, EarlyView.
Precise control over guanine crystal morphology is achieved through biologically inspired, facet‐selective interactions. Simple synthetic polymers tune growth from prisms to needles and plate‐like biogenic forms by modulating multivalency, polarity, and functional‐group identity.
Dolev Brenman‐Begin   +11 more
wiley   +1 more source

Dismantling the genus Tarenna (Rubiaceae: Pavetteae) in Africa and Madagascar, with the description of three new genera

open access: yesTAXON, EarlyView.
Abstract As presently circumscribed, the Paleotropical genus Tarenna, belonging to the tribe Pavetteae (Rubiaceae), comprises about 200 species and has its centres of diversity in tropical Asia and Africa. Previous molecular phylogenetic studies of the tribe revealed the polyphyly of Tarenna, suggesting that the genus needs to be recircumscribed ...
Petra De Block   +3 more
wiley   +1 more source

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