Results 1 to 10 of about 262,384 (107)

Solid-Phase Optical Sensing Techniques for Sensitive Virus Detection [PDF]

Sensors, 2023
Viral infections can pose a major threat to public health by causing serious illness, leading to pandemics, and burdening healthcare systems. The global spread of such infections causes disruptions to every aspect of life including business, education ...
Elif Seymour, Fulya Ekiz Kanik, Sinem Diken Gür, Monireh Bakhshpour-Yucel, Ali Araz, Nese Lortlar Ünlü, M. Selim Ünlü   +6 more
doaj   +3 more sources

A Novel Urine Test Biosensor Platform for Early Lung Cancer Detection. [PDF]

Biosensors (Basel), 2023
Lung cancer is the leading cause of cancer-related mortality worldwide. Early detection is essential to achieving a better outcome and prognosis. Volatile organic compounds (VOCs) reflect alterations in the pathophysiology and body metabolism processes ...
Wiesel O, Sung SW, Katz A, Leibowitz R, Bar J, Kamer I, Berger I, Nir-Ziv I, Mark Danieli M.   +8 more
europepmc   +2 more sources

Multiplexed, High-Sensitivity Measurements of Antibody Affinity Using Interferometric Reflectance Imaging Sensor

Biosensors, 2021
Anthrax lethal factor (LF) is one of the enzymatic components of the anthrax toxin responsible for the pathogenic responses of the anthrax disease. The ability to screen multiplexed ligands against LF and subsequently estimate the effective kinetic rates
Allison M. Marn, James Needham, Elisa Chiodi, M. Selim Ünlü   +3 more
doaj   +2 more sources

Plasma membrane H⁺-ATPase activation increases global transcript levels and promotes the shoot growth of light-grown Arabidopsis seedlings. [PDF]

Plant J
SUMMARY Plant cell growth requires the elongation of cells mediated by cell wall remodelling and turgor pressure changes. The plasma membrane (PM) H+‐ATPase facilitates both cell wall loosening and turgor pressure changes by acidifying the apoplast of cells, referred to as acid growth.
Kinoshita SN, Taki K, Okamoto F, Nomoto M, Takahashi K, Hayashi Y, Ohkanda J, Tada Y, Finkemeier I, Kinoshita T.   +9 more
europepmc   +2 more sources

Multimodal Nanoplasmonic and Fluorescence Imaging for Simultaneous Monitoring of Single-Cell Secretory and Intracellular Dynamics. [PDF]

Adv Sci (Weinh)
This study leverages the complementary advantages of label‐free nanoplasmonic biosensing and multichannel fluorescence microscopy to develop a multimodal imaging system for real‐time, spatiotemporal monitoring of cellular activities at the single‐cell level.
Ansaryan S, Chiang YC, Liu YC, Reichenbach P, Irving M, Altug H.   +5 more
europepmc   +2 more sources

Generation of Conformation-Specific Monoclonal Antibodies for Integral Membrane Proteins. [PDF]

Curr Protoc
Abstract Antibodies and their antigen‐binding fragments, including fragment antigen‐binding domains (Fabs) and single‐chain variable fragments (scFvs), are extraordinary tools in all fields of biology, particularly in neuroscience, where they have been utilized for imaging, detection, and quantification studies.
Sheldon N, Dhandapani G, Kim J, Spangler CJ, Fang C, Park J, Rao P, Gouaux E.   +7 more
europepmc   +2 more sources

A Compact Prism-Based Microscope for Highly Sensitive Measurements in Fluid Biopsy. [PDF]

J Biophotonics
The growing need for portable, affordable disease detection has led to the development of advanced biosensors. We created a prism‐based total internal reflection system with gold nanoparticles to enable highly sensitive, rapid detection of analytes.
Perego L, Dallari C, Falciani C, Pini A, Gardini L, Credi C, Pavone FS.   +6 more
europepmc   +2 more sources

Electrochemiluminescent nanostructured DNA biosensor for SARS-CoV-2 detection. [PDF]

Talanta, 2022
Gutiérrez-Gálvez L, Del Caño R, Menéndez-Luque I, García-Nieto D, Rodríguez-Peña M, Luna M, Pineda T, Pariente F, García-Mendiola T, Lorenzo E.   +9 more
europepmc   +2 more sources

Phloretin, an Apple Phytoalexin, Affects the Virulence and Fitness of Pectobacterium brasiliense by Interfering With Quorum-Sensing

Frontiers in Plant Science, 2021
The effects of phloretin a phytoalexin from apple, was tested on Pectobacterium brasiliense (Pb1692), an emerging soft-rot pathogen of potato. Exposure of Pb1692 to 0.2 mM phloretin a concentration that does not affect growth, or to 0.4 mM a 50% growth ...
Man-in Pun, N. Khazanov, Ortal Galsurker, M. Weitman, Z. Kerem, H. Senderowitz, I. Yedidia   +6 more
semanticscholar   +1 more source

Volatile anesthetics inhibit presynaptic cGMP signaling to depress presynaptic excitability in rat hippocampal neurons

Neuropharmacology, 2022
Volatile anesthetics alter presynaptic function including effects on Ca2+ influx and neurotransmitter release. These actions are proposed to play important roles in their pleiotropic neurophysiological effects including unconsciousness and amnesia.
Iris A. Speigel, Kishan Patel, V. Osman, H. Hemmings   +3 more
semanticscholar   +1 more source