Results 41 to 50 of about 272,711 (168)

Fully Synthetic Longitudinal Real-World Data From Hearing Aid Wearers for Public Health Policy Modeling [PDF]

, 2019
Here, we share the first outcome of EVOTION (www.h2020evotion.eu) in the form of a data-set to inspire, encourage, and motivate a data-driven analytical approach to evidence-based healthcare policy modeling using real-world longitudinal data.
Anisetti, M., Bamiou, D-E., Bibas, T., Bossing, R., Christensen, J. H., Dimakopoulos, N., Ecomomou, A., Giotis, G., Kikidiks, D., Murdin, L., Pontoppidan, N. H., Spanoudakis, G.   +11 more
core   +2 more sources

Dose individualisation of antibiotics in critically ill patients with inflammation: A narrative review

British Journal of Clinical Pharmacology, Volume 91, Issue 11, Page 3042-3053, November 2025.
Due to extensive pathophysiological changes in critically ill patients, standard dosing of antibiotics may lead to inadequate drug exposure. This is concerning, as insufficient plasma drug concentrations may lead to treatment failure, whereas excessive drug exposure may increase the risk of toxic adverse events.
Sarah Dräger, Iris K. Minichmayr, Narges Alipanah‐Lechner, Erin F. Barreto, Lieuwe D. J. Bos, Lucas M. Fleuren, Nicole G. M. Hunfeld, Sumith K. Mathew, Sophie L. Stocker, João Paulo Telles, Antoni Torres, Birgit C. P. Koch, Henrik Endeman   +12 more
wiley   +1 more source

Iris Recognition Development Techniques: A Comprehensive Review

Complex, 2021
Recently, iris recognition techniques have achieved great performance in identification. Among authentication techniques, iris recognition systems have received attention very much due to their rich iris texture which gives robust standards for ...
Jasem Rahman Malgheet, N. Manshor, L. S. Affendey   +2 more
semanticscholar   +1 more source

A digital shadow of CAR T cell expansion in a perfusion bioreactor: Informing optimal harvest times for autologous cell therapy

Biotechnology Progress, Volume 41, Issue 6, November/December 2025.
Using online metabolite data from the first few days of a bioreactor run, the digital shadow can forecast the cell concentration in real‐time with an accuracy of 13% (standard deviation ≈ 6%). These predictions can guide the optimal harvest time of CAR T cells for subsequent re‐infusion into the patient.
Joseph R. Egan, Núria Marí‐Buyé, Elia Vallejo Benítez‐Cano, Miquel Costa, Linda Wanika, Michael J. Chappell, Ursula Schultz, Jelena Ochs, Manuel Effenberger, David Horna, Qasim Rafiq, Stephen Goldrick   +11 more
wiley   +1 more source

Stimuli‐responsive systems: A focus on controlled drug delivery for posterior segment ocular disease

Responsive Materials, Volume 3, Issue 4, November 2025.
This review highlights recent advances in stimuli‐responsive drug delivery for posterior segment diseases, focusing on mechanisms and potential. It also explores mechanically interlocked molecules and bioorthogonal reactions as novel approaches. Challenges and future perspectives are discussed, aiming to bridge the gap between research and clinical ...
Chengzhi Zhang, Jiayi Hou, Yameng Zhao, Yiwen Wang, Kexin Wang, Siyu Li, Yange Wang, Jiehao Zhang, Shenao Ding, Chenxu Zhang, Zongming Song, Ye Tao   +11 more
wiley   +1 more source

Oral Delivery of Chitosan‐Rosmarinic Acid Nanoparticles Ameliorates Mucosal Inflammation in a Mouse Model of Colitis

Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
Orally administered low molecular weight chitosan–rosmarinic acid nanoparticles demonstrate potent anti‐inflammatory effects in a mouse model of colitis by scavenging reactive oxygen species, preserving intestinal barrier integrity, and modulating immune responses, underscoring their promise as an effective nanomedicine for inflammatory bowel disease ...
Afia Tasnim Rahman, Sungyeon Kang, Sangyong Jon   +2 more
wiley   +1 more source

Deep Learning Approach for Multimodal Biometric Recognition System Based on Fusion of Iris, Face, and Finger Vein Traits

Italian National Conference on Sensors, 2020
With the increasing demand for information security and security regulations all over the world, biometric recognition technology has been widely used in our everyday life.
Nada Alay, Heyam H. Al-Baity
semanticscholar   +1 more source

Photosynthesis-dependent H₂O₂ transfer from chloroplasts to nuclei provides a high-light signalling mechanism [PDF]

, 2017
Chloroplasts communicate information by signalling to nuclei during acclimation to fluctuating light. Several potential operating signals originating from chloroplasts have been proposed, but none have been shown to move to nuclei to modulate gene ...
A Vuleta, C Grefen, CC Winterbourn, CH Foyer, D Wagner, DE Fomenko, F Guerineau, G Creissen, G Curien, G Galvez-Valdivieso, G Miller, G Queval, GP Bienert, H Jung, HS Marinho, HW Heldt, I Pérez-Salamó, I Sparkes, J Awad, J Shaikhali, J Waring, JL Caplan, JL Erickson, JO Brunkard, K Asada, K Athanasiou, K Bobik, K Tamura, KA Morano, KN Markvicheva, L Michelet, L Rizhsky, M Exposito-Rodriguez, M Gorecka, M Gutscher, M Malinouski, M Page, M Schwarzländer, M Shirao, M Tantama, MCF Proctor, ME Matlashov, MM Mubarakshina, MO Vogel, N Otsu, N Smirnoff, N Suetsugu, N Suzuki, NM Mishina, NR Baker, O Voinnet, PJ Gollan, R Scheibe, RM Larkin, RP Hellens, S Eberhard, S Karpinski, S Karpinski, S Kitajima, S Vandenabeele, SM Driever, T Lawson, T Maruta, T Selga, VV Belousov, Y Xing, YN Munekage   +66 more
core   +1 more source

Spatiotemporal Interrogation of Single Spheroids Using Multiplexed Nanoplasmonic‐Fluorescence Imaging

Small Methods, Volume 9, Issue 10, October 1, 2025.
This work introduces a multiplexed imaging platform that integrates nanoplasmonic sensing with fluorescence microscopy for concomitant monitoring of extraspheroid secretions and intraspheroid features over extended periods with spatiotemporal resolution.
Saeid Ansaryan, Yung‐Cheng Chiang, Yen‐Cheng Liu, Jiayi Tan, Luis Francisco Lorenzo‐Martín, Matthias P. Lutolf, Genrich Tolstonog, Hatice Altug   +7 more
wiley   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, Volume 14, Issue 23, September 8, 2025.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source