Results 221 to 230 of about 161,243 (325)

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Near‐resonant excitation of the Adriatic barotropic modes: The seiche events of December 2019

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
This study examines severe flooding in the northern Adriatic Sea in December 2019, which existing forecasting systems failed to predict. Analysis of wind and sea‐level data, alongside reanalysis datasets and a high‐resolution hydrodynamic model, revealed a wind‐induced resonance mechanism.
Marco Bajo   +3 more
wiley   +1 more source

Coupled ferroelectric-anisotropic optoelectronic synapse for polarization-sensitive neuromorphic vision. [PDF]

open access: yesNat Commun
Huo J   +8 more
europepmc   +1 more source

Actuation Strategies for Underwater Jet‐Propelled Soft Robots

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT This review article examines jet‐propulsion mechanisms in underwater soft robotic systems, focusing exclusively on physically fabricated and experimentally validated robots. Covering research published from 2013 to 2025, this study classifies and evaluates jet‐propulsion robots based on their actuation mechanisms.
Angel Kitone   +3 more
wiley   +1 more source

Integrated LEO Constellation and In‐Cabin Distribution System for Continuous Aircraft 5G Connectivity

open access: yesInternational Journal of Satellite Communications and Networking, EarlyView.
ABSTRACT The integration of low Earth orbit (LEO) satellite constellations with commercial aircraft communication systems presents critical challenges in maintaining continuous connectivity during dynamic flight conditions. Current geostationary satellite systems suffer from high round‐trip latency (>$$ > $$ 500 ms) and inadequate coverage at high ...
Raúl Parada   +4 more
wiley   +1 more source

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