Results 21 to 30 of about 359,102 (245)
BJGP Open, 2021 Background: Primary care has a vital role in supporting patient autonomy to enable people with long-term conditions to manage their own health and wellness.
Claire Collins +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Understanding and Mis-understanding in Language in Brian O’Nolan’s An Béal Bocht and Cruiskeen Lawn [PDF]
Estudios Irlandeses, 2020 Brian O’Nolan, part of the so-called Irish Modernism that arose at the same time as the declaration of the Republic, finds his literary form traversed by the question of Irish identity and materializes it in the “awesome jaggedness and seeming ...
Julieta Abella
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The Irish Maritime Transport Economist Volume 4 [PDF]
, 2007 The Irish Maritime Development Office (IMDO) of the Marine Institute publishes the Irish Maritime Transport Economist each year to provide a descriptive statistical analysis of the Irish ports and shipping services sector, as well as the many factors ...
Irish Maritime Development Office
core
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
The Irish Maritime Transport Economist Volume 2 [PDF]
, 2005 The Irish Maritime Transport Economist (IMTE) aims to provide Irish companies involved in International trade with a single journal that provides and collates relevant statistical economic, trade, traffic and shipping market information. The focus of the
Irish Maritime Development Office
core
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Simple Event nominals with Argument Structure? – Evidence from Irish deverbal nominalizations
Zeitschrift für Wortbildung, 2020 Deverbal nominals in Irish support Grimshaw's (1990) tripartite division into complex event (CE-), simple event (SE-) and result nominals (R-nominals). Irish nominals are ambiguous only between the SE- and R-status.
Maria Bloch-Trojnar
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source